7332-97-0Relevant academic research and scientific papers
Palladium-Catalyzed Synthesis of 1,2-Diketones from Aryl Halides and Organoaluminum Reagents Using tert-Butyl Isocyanide as the CO Source
Chen, Bo,Wu, Xiao-Feng
supporting information, p. 636 - 641 (2020/01/31)
In this work, an interesting and practical procedure for the synthesis of 1,2-diketones from aryl halides and organoaluminum reagents has been developed. Employing tert-butyl isocyanide as the CO source and palladium as the catalyst, the desired 1,2-diketones were isolated in good to excellent yields with good functional group tolerance. Concerning the reaction partners, besides aryl halides, both alkyl- A nd arylaluminum reagents were all suitable substrates here.
Ruthenium-catalyzed oxidation of alkenes at room temperature: A practical and concise approach to α-diketones
Chen, Shulin,Liu, Zhaojun,Shi, Erbo,Chen, Long,Wei, Wei,Li, Hong,Cheng, Yannan,Wan, Xiaobing
supporting information; experimental part, p. 2274 - 2277 (2011/06/27)
Chemical equations presented. The catalytic oxidation of alkenes to α-diketones is unprecedented. A new oxidation of alkenes, catalyzed by a ruthenium complex, which allows an efficient route to α-diketones using TBHP as an oxidant is described. This methodology is highly functional group tolerant, is practically convenient, requires no additional ligand, and operates under mild conditions with short reaction times. Based upon experimental observations, a plausible mechanism is proposed.
