7333-52-0

Usage

Uses

Used in Organic Synthesis:
Cyclopentyltriphenylphosphonium bromide is used as a phase transfer catalyst for facilitating reactions between immiscible reactants, which is crucial in organic synthesis. Its ability to transfer reactants between phases allows for more efficient and effective reactions to occur.
Used in Williamson Ether Synthesis:
In the Williamson ether synthesis, Cyclopentyltriphenylphosphonium bromide is employed as a catalyst to promote the nucleophilic substitution reaction between an alkoxide ion and an alkyl halide, leading to the formation of ethers.
Used in Nucleophilic Substitution Reactions:
Cyclopentyltriphenylphosphonium bromide is utilized as a catalyst in nucleophilic substitution reactions, where it aids in the reaction between a nucleophile and an electrophile, enhancing the reaction rate and selectivity.
Used in Alkylation Reactions:
In alkylation reactions, Cyclopentyltriphenylphosphonium bromide serves as a phase transfer catalyst, enabling the reaction between an alkyl halide and a nucleophile, which is particularly useful in the synthesis of complex organic molecules.
Used in Pharmaceutical and Fine Chemicals Synthesis:
Cyclopentyltriphenylphosphonium bromide is used as a catalyst in the synthesis of pharmaceuticals and other fine chemicals, where its phase transfer capabilities are essential for the efficient production of desired compounds.

InChI:InChI=1/C23H24P.BrH/c1-4-12-20(13-5-1)24(23-18-10-11-19-23,21-14-6-2-7-15-21)22-16-8-3-9-17-22;/h1-9,12-17,23H,10-11,18-19H2;1H/q+1;/p-1

Upstream product

• 137-43-9 Cyclopentyl bromide 
• 603-35-0 triphenylphosphine 
• 110-52-1 1,4-dibromo-butane 
• 19493-09-5 Methylenetriphenylphosphorane 
• 4399-47-7 Bromocyclobutane 

Downstream Products

• 85477-46-9 2-Cyclopentyliden-2-methoxythioessigsaeure-O-methylester 
• 3878-45-3 triphenylphosphine sulfide 
• 111653-80-6 o-(1,3-dioxolan-2-yl)benzylidenecyclopentane 
• 1026382-20-6 4-[3-Cyclopentylidenemethyl-6-(2-ethyl-butylcarbamoyl)-indol-1-ylmethyl]-3-methoxy-benzoic acid methyl ester 
• 21482-00-8 Cyclopentylidene-triphenyl-λ⁵-phosphane 
• 4410-77-9 benzylidenecyclopentane 
• 137734-08-8 Benzoic acid 1-cyclopentylidene-2,2,2-trifluoro-ethyl ester 
• 2107-77-9 4-methyldaphnetin 
• 445039-33-8 5-cyclopentylidenemethyl-6-(4-methanesulfonyl-phenyl)-benzo[1,3]dioxole 
• 530144-92-4 1-(benzyloxy)-3-(cyclopentylidenemethyl)benzene 
• 119395-63-0 1-chloro-4-(cyclopentylidenemethyl)-benzene 
• 92078-69-8 1-(cyclopentylidenemethyl)-4-fluorobenzene 
• 10299-81-7 1-(cyclopentylidenemethyl)-2-nitrobenzene 
• 82571-92-4 1-(cyclopentylidenemethyl)-4-nitrobenzene 

Relevant academic research and scientific papers

THERAPEUTIC COMPOUNDS

The present disclosure relates to compounds of formula (I) and pharmaceutically acceptable salts thereof, and compositions and uses thereof. The compounds are useful as inhibitors of the YAP:TEAD protein:protein interaction. Also included are pharmaceutical compositions comprising a compound of formula (I) or a pharmaceutically acceptable salt thereof, and methods of using such compounds and salts in the treatment of various YAP:TEAD-mediated disorders, including cancer.

Containing difluoro methylene key bridge of the liquid crystal compound and its preparation method and composition

The invention discloses a liquid crystal compound containing difluoro-methylene key bridge, a preparation method of the liquid crystal compound containing difluoro-methylene key bridge and a composition containing the liquid crystal compound. The liquid c

Synthesis of 2,3-Disubstituted Quinolines via Ketenimine or Carbodiimide Intermediates

Cyclopenta[b]quinolines and cyclohexa[b]quinolines were prepared via the reactions of α-diazo ketones with N-(2-cyclopropylidenemethylphenyl)phosphanimines and N-(2-cyclobutylidenemethylphenyl) phosphanimine, respectively. The reaction proceeds in a cascade involving ketenimine formation, 6 π-electron ring closure, and 1,3-alkyl shift. A similar approach was developed for the synthesis of dihydropyrrolo-[2,3-b]quinolines from N-(2-cyclopropylidenemethylphenyl)phosphanimines and isocyanates.

Negative Dielectric Anisotropic Liquid Crystal Compounds Containing 2,3-Difluorophenyl Group, and Preparation Method and Use Thereof

A negative dielectric anisotropic liquid crystal compound containing 2,3-difluorophenyl, and a preparation method and use thereof are disclosed. The compound has a general structural formula as shown in Formula I. The negative dielectric anisotropic liquid crystal compound has a negative dielectric anisotropy (Δε), and has cyclobutyl or cyclopentyl as a terminal group. Compared with conventional liquid crystal compounds with a flexible alkyl chain as a terminal group, the compound of Formula I according to the present invention has the advantage of high clearing point, and enables extension of the application range of a liquid crystal mixture because a positive correlation exists between the clearing points of the liquid crystal mixture and monomer liquid crystal compounds. In addition, the compound can increase the absolute value of the negative dielectric constant of the liquid crystal mixture, thus having an important application value.

OXASPIRO [2.5] OCTANE DERIVATIVES AND ANALOGS

The invention provides oxaspiro[2.5]octane derivatives and analogs, methods for preparation thereof, intermediates thereto, pharmaceutical compositions, and uses thereof in the treatment of various disorders and conditions, such as overweight and obesity.

A New Photochemical Synthesis of Cyclopropanecarboxylic Acids Present in Pyrethroids by the Aza-di-?-methane Rearrangement

A novel synthetic route to chrysanthemic acid, 2-cyclopentylidenmethyl-3,3-dimethylcyclopropanecarboxylic acid, fluorenespiro-2,2-dimethylcyclopropanecarboxylic acid and indenespiro-2,2-dimethylcyclpropanecarboxylic acid, all of them present in pyrethroids of known insecticidal activity, is described.The key step in the synthesis is the aza-di-?-methane rearrangement of some 1-aza-1,4,6-trienes and some 1-aza-1,4-dienes, using triplet sensitization.

Novel phenylacetic acid derivatives

Phenylacetic acid derivatives of the formula STR1 wherein n is an integer of 2 to 5; STR2 R1 is hydrogen, halogen, trifluoromethyl, nitro or amino; R2 and R3 each independently is hydrogen or lower alkyl; or together form an ethylene group; X1 represents two hydrogen atoms or an oxo group; and Y1 is cyano, hydroxyamidocarbonyl, carbamoyl, 5-tetrazolyl or carboxyl; and for derivatives wherein Y is carboxyl, salts thereof with physiologically compatible bases, esters thereof from physiologically acceptable alcohols and amides thereof from physiologically acceptable amines have valuable pharmacological activity, e.g., as antiinflammatory agents.