73334-58-4

Basic information

• Product Name: 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,2-dihydro- (9CI)
• Synonyms: 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,2-dihydro- (9CI);4H-Pyrazolo[3,4-d]pyriMidin-4-one, 1,2-dihydro-;1,2-dihydropyrazolo[3,4-d]pyrimidin-4-one
• CAS NO: 73334-58-4
• Molecular Formula: C₅H₄N₄O
• Molecular Weight: 136.11146
• Product Categories: PYRIMIDINE
• Mol File: 73334-58-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 290.8±23.0 °C(Predicted)
• Appearance: /
• Density: 1.89±0.1 g/cm3(Predicted)
• PKA: 4.56±0.20(Predicted)
• CAS DataBase Reference: 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,2-dihydro- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,2-dihydro- (9CI)(73334-58-4)
• EPA Substance Registry System: 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,2-dihydro- (9CI)(73334-58-4)

Safety Data

• Hazardous Substances Data: 73334-58-4(Hazardous Substances Data)

Usage

General Description

4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,2-dihydro- (9CI) is a chemical compound with the molecular formula C7H6N4O. It is a heterocyclic compound containing a pyrazolo-pyrimidinone ring system, and it exists as a 1,2-dihydro-derivative. 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,2-dihydro- (9CI) is commonly used in pharmaceutical and medicinal chemistry as a building block for the synthesis of various bioactive molecules. It may also have potential therapeutic applications due to its structural features and ability to interact with biological targets. Additionally, it has been studied for its potential use as an anti-cancer agent and may have other pharmacological activities as well.

Upstream product

• 27511-79-1 3-amino-4-pyrazolocarboxamide hemisulfate 
• 77287-34-4 formamide 

Downstream Products

• 79570-57-3 1-(hydroxymethyl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one 
• 5399-92-8 4-chloro-1H-pyrazolo[3,4-d]pyrimidine 

Relevant articles and documents

Pyrazolo [3, 4 - d] pyrimidines of the synthesis process

The invention relates to a synthesis process of pyrazolo[3,4-d]pyrimidine compounds. The synthesis process comprises the following steps: (1) adding 3-aminopyrazole-4-carboxamide hemisulfate and methanamide into a reaction kettle, adjusting the pH value to 1.6-3.8, heating to react, and cooling to the room temperature; (2) standing the product obtained in the step (1) at 5-10 DEG C and crystallizing; (3) filtering, transferring rough crystals into a pulping kettle, adding purified water, pulping, and washing; and (4) filtering again, discarding filtrate, washing filter cake with purified water until the pH value of eluate is higher than or equal to 6, and drying to obtain white 4-hydroxypyrazolo[3,4-d]pyrimidine. According to the synthesis process, synthesis operation steps and difficulty are simplified, the cost of inert gas shielding is avoided; and meanwhile, the synthesis process is applicable to the synthesis of 4-mercaptopyrazolo[3,4-d]pyrimidine, so that the synthesis process is applicable to the large-scale industrial synthesis application.