73348-44-4Relevant academic research and scientific papers
STUDY OF KINETICS AND MECHANISM OF SULFONATION OF THIOPHENE AND ITS DERIVATIVES BY COMPLEX COMPOUNDS OF SULFURIC ANHYDRIDE
Shustareva, T. K.,Druzhinina, V. E.
, p. 28 - 33 (1986)
By quantitavely studying the sulfonation of thiophene and its homologs by complexes of sulfuric anhydride with ethers, amides and trialkyl phosphates it was possible to determine kinetic and thermodynamic parameters of the process, to propose a SE2 type reaction mechanism and also to reveal a quantitative dependence of the rate constant of the sulfonation reaction of thiophene on the basicity of the complex-forming agent: The sulfonating activity of the complexes studied increses in the series - amides trialkyl phosphates ethers, which is the reverse of the increase in the basicity series of a donor.
Coordination complexes of platinum useful as antiproliferative agents
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, (2008/06/13)
Platinum complexes are disclosed in which the platinum cation is coordinated to heterocyclic sulfur compounds as well as monodentate or bidentate amines. The complexes have the formula: STR1 wherein L1 and L2 are individually ammonia or monodentate amine ligands or L1 and L2 together are a bidentate amine ligand, S* is sulfur and R1 and R2 taken together with S are thiophene, thiazole, benzothiazole or benzothiophene. These platinum complexes, which have anti-neoplastic activity, are synthesized by reacting sulfonated heterocyclic sulfur compounds with diamines of platinum nitrate.
