7336-34-7

Basic information

• Product Name: (S)-7α-Acetylamino-6,7-dihydro-3,10-dihydroxy-1,2-dimethoxybenzo[a]heptalen-9(5H)-one
• Synonyms: (S)-7α-Acetylamino-6,7-dihydro-3,10-dihydroxy-1,2-dimethoxybenzo[a]heptalen-9(5H)-one;Alkaloid L-5
• CAS NO: 7336-34-7
• Molecular Formula: C20H21NO6
• Molecular Weight: 371.38384
• Mol File: 7336-34-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (S)-7α-Acetylamino-6,7-dihydro-3,10-dihydroxy-1,2-dimethoxybenzo[a]heptalen-9(5H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-7α-Acetylamino-6,7-dihydro-3,10-dihydroxy-1,2-dimethoxybenzo[a]heptalen-9(5H)-one(7336-34-7)
• EPA Substance Registry System: (S)-7α-Acetylamino-6,7-dihydro-3,10-dihydroxy-1,2-dimethoxybenzo[a]heptalen-9(5H)-one(7336-34-7)

Safety Data

• Hazardous Substances Data: 7336-34-7(Hazardous Substances Data)

Upstream product

• 7336-33-6 3-demethylcolchicine 
• 477-29-2 3-de-O-methylcolchicine-3-O-β-Dglucopyranoside 

Relevant articles and documents

PHENOLIC CONGENERS OF COLCHICINE: PREPARATION AND CHARACTERIZATION OF PHENOLIC AND CATECHOLIC ANALOGUES OF COLCHICINE, COLCHICEINE AND THIOCOLCHICINE

Treatment of 2-demethylcolchicine (2) with sulfuric acid afforded 1,2-didemethylcolchicine (6) as the major, and 2,3-didemethylcolchicine (8) as the minor product. 2,3-Didemethylcolchicine (8) was prepared from 3-ethoxycarbonyl-3-demethylcolchicine by sulfuric acid treatment.Hydrolysis of catecholic compounds 6 and 8 with 0.1 N hydrochloric acid afforded colchiceines 13 and 14, respectively.Ester derivatives of 2-demethyl- and 3-demethylcolchicine, and of catechols 6 and 8 were prepared.A direct conversion of 3 into 3-demethylthiocolchicine (15) and conversion of 15 into ester derivatives is described.Cleavage of the ether groups of colchicine by boron tribromide is also reported.