733769-88-5

Upstream product

• 94790-24-6 (2R)-tert-butoxycarbonylamino-3-(4-methoxyphenyl)propionic acid methyl ester 
• 76757-90-9 N-(tert-butoxycarbonyl)-D-tyrosine methyl ester 

Downstream Products

• 733769-83-0 (S)-2-{3-[(R)-2-Acryloylamino-3-(4-methoxy-phenyl)-propionylamino]-propionyloxy}-4-methyl-pentanoic acid (S)-1-[(S)-1-((2R,3R)-3-phenyl-oxiranyl)-ethyl]-but-3-enyl ester 
• 733769-90-9 (S)-2-{3-[(R)-2-Acryloylamino-3-(4-methoxy-phenyl)-propionylamino]-propionyloxy}-4-methyl-pentanoic acid tert-butyl ester 
• 1026015-46-2 (S)-2-{3-[(R)-2-Acryloylamino-3-(4-methoxy-phenyl)-propionylamino]-propionyloxy}-4-methyl-pentanoic acid 
• 1027261-48-8 3-[(R)-2-Acryloylamino-3-(4-methoxy-phenyl)-propionylamino]-propionic acid ethyl ester 
• 733769-89-6 3-[(R)-2-Acryloylamino-3-(4-methoxy-phenyl)-propionylamino]-propionic acid 
• 162600-54-6 cryptophycin-24 

Relevant academic research and scientific papers

RCM approach for the total synthesis of cryptophycin-24 (Arenastatin A)

An efficient total synthesis of cryptophycin-24 (arenastatin A) is reported, which features two novel synthetic strategies, the use of a RCM reaction to form the macrocycle, and the introduction of the styrene epoxide moiety prior to the macrocyclization