73384-11-9Relevant articles and documents
Discovery of 3,3′-(2,4-diaminopteridine-6,7-diyl)diphenol as an isozyme-selective inhibitor of PI3K for the treatment of ischemia reperfusion injury associated with myocardial infarction
Palanki, Moorthy S. S.,Dneprovskaia, Elena,Doukas, John,Fine, Richard M.,Hood, John,Kang, Xinshan,Lohse, Dan,Martin, Michael,Noronha, Glenn,Soll, Richard M.,Wrasidlo, Wolfgang,Yee, Shiyin,Zhu, Hong
, p. 4279 - 4294 (2008/02/13)
In studies aimed toward identifying effective and safe inhibitors of kinase signaling cascades that underlie ischemia/reperfusion (I/R) injury, we synthesized a series of pteridines and pyridopyrazines. The design strategy was inspired by the examination
On the Amination of Pteridines by Liquid Ammonia-Potassium Permanganate
Sladowska, H.,De Meester, J. W. G.,Plas, H. C. van der
, p. 477 - 480 (2007/10/02)
7-Phenyl, 7-(p-methoxyphenyl)-, 7-methyl-, 7-t-butyl-, 6,7-diphenyl-, 6,7-dimethyl- and 2-phenylpteridine are converted in good yields into their respective 4-amino compounds, when they are dissolved in liquid ammonia (-40 deg) and potassium permanganate
