73389-49-8

Upstream product

• 6562-21-6 3β-(Acetyloxy)-5α-cholest-8(14)-ene 
• 20780-35-2 5α-cholest-14-en-3β-ol 
• 83681-87-2 5α-cholestane-3β,15β-diol 3-(dimethyl-tert-butylsilyl) ether 15-(ethyl carbonate) 
• 80-99-9 lathosterol 
• 83681-85-0 (3S,5S,8R,9S,10S,13R,14S,15R,17R)-3-(tert-Butyl-dimethyl-silanyloxy)-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-15-ol 
• 83681-84-9 5α-cholest-14-en-3β-ol dimethyl-tert-butylsilyl ether 
• 83681-85-0 5α-cholestane-3β,15α-diol 3-(dimethyl-tert-butylsilyl) ether 

Relevant academic research and scientific papers

Inhibitors of sterol synthesis. Synthesis and spectral properties of 3β-hydroxy-5α-cholestan-15-one and its 14β-epimer and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity

3β-Hydroxy-5α-cholestan-15-one (2a) and its 14β-epimer 2b were prepared from 3β-acetoxy-5α-cholest-8(14)-ene (3). Hydroboration of 3 at 45-50°C gave a mixture of 5α,14α-cholestane-3β,15α-diol and 5α,14β-cholestane-3β,15β-diol, which were separated on sili

Sterols in Marine Invertebrates. 32. Isolation of 3β-(Hydroxymethyl)-A-nor-5α-cholest-15-ene, the First Naturally Occurring Sterol with a 15-16 Double Bond

A new A-nor sterol, 3β-(hydroxymethyl)-A-nor-5α-cholest-15-ene, with an unusual unsaturation in the Δ15 position has been found in the Pacific sponge Homaxinella trachys together with ten other A-nor sterols.The structure was elucidated by 360-MHz 1H NMR, 13C NMR, and mass spectral analysis as well as by chemical interconversion and comparision with synthetic 5α-cholest-15-en-3β-ol. 13C NMR spectra of the title compound and of various 3β-(hydroxymethyl)-A-nor-5α-cholestanes were assigned as an aid in future structure elucidation of this class of sterols.