73391-97-6Relevant academic research and scientific papers
Synthesis of γ-lactams via Ru(II)–Pheox-catalyzed regioselective intramolecular Csp3–H insertion of diazoacetamides
Fujii, Takuji,Thu, Huong Dang Thi,Iwasa, Seiji
supporting information, (2020/08/19)
Herein, γ-lactam derivatives are obtained in high yield via highly regioselective intramolecular Csp3–H insertion reactions of α-diazoacetamides catalyzed by a rac-Ru(II)–Pheox complex. The catalytic system is applicable to a wide range of diaz
9H-Pyridu ((3,4-b) indole derivatives
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, (2008/06/13)
9H-Pyrido?3,4-b!indole compounds have a pronounced leukotriene-B4 antagonistic action, and thus show a completely different spectrum of activity than known β-carbolines.
Structure-activity relationships study of two series of leukotriene B4 antagonists: Novel indolyl and naphthyl compounds substituted with a 2- [methyl(2-phenethyl)amino]-2-oxoethyl side chain
Chan, Wan K.,Huang, Fu-Chih,Morrissette, Matthew M.,Warus, James D.,Moriarty, Kevin J.,Galemmo, Robert A.,Dankulich, William D.,Poli, Gregory,Sutherland, Charles A.
, p. 3756 - 3768 (2007/10/03)
N-Methyl-N-phenethylphenylacetamide has been reported to be a key binding domain to LTB4 receptors. Here we describe the synthesis and structure-activity relationship (SAR) studies of two new series of LTB4 receptor antagonists in wh
SUBSTITUTED MONOCYCLIC ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B4 ANTAGONIST ACTIVITY
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, (2008/06/13)
Monocyclic aryl compounds having selective LTB 4 antagonists properties and comprising an amido substituent, a substituent group having a terminal carboxylic acid or derivative thereof and a lipophilic substituent, therapeutic compositions and methods of treatment of disorders which result from LTB. sub.4 activity using the monocyclic aryl compounds are disclosed.
