73393-27-8Relevant articles and documents
Polycondensation of Long-chain Esters of Aromatic Amino Acids in Monolayer at the Air/water Interface
Liu, Ming-hua,Nakahara, Hiroo,Shibasaki, Yoshio,Fukuda, Kiyoshige
, p. 967 - 970 (1993)
Polycondensation of octadecyl esters of aromatic amino acids (L-TrpC18, L-TyrC18, L-PheC18) can be markedly accelerated in the monolayers on the aqueous subphase of pH 8.The reaction rate was ten times or more faster than in the bulk solid.There exist optimum molecular packing and orientation for the polycondensation.The resultant poly-amino acids take α-helix and/or random coil conformations.
A Simple Method for the Synthesis of Long-Chain Alkyl Esters of Amino Acids
Penney, Christopher L.,Shah, Pravinkant,Landi, Silvio
, p. 1457 - 1459 (2007/10/02)
A practical one step procedure is described for the synthesis of long-chain alkyl esters of amino acids.A number of octadecyl (stearyl) amino acids were made in moderate to high overall yields of 40-90percent via methanesulfonic acid catalyzed esterification in an octadecanol melt.No special anhydrous conditions or N-protected amino acids were required and so in the case of lower product yields the synthesis was still desirable relative to alternative methodologies.Further, simpler routes gave lower yields.A correlation was observed between reactant hydrophilicity and product yields.
