73410-98-7Relevant academic research and scientific papers
Enzymatic synthesis of glucoside derivatives of validamine and valienamine
Furumoto,Kameda,Matsui
, p. 1871 - 1875 (2007/10/02)
α- And β-glucoside derivatives of validamine and valienamine were prepared by enzymatic transglucosidation using α- and β-glucosidase of Rhodotorula lactosa. The structures of these derivatives have been elucidated by 13C- and 1H-nuclear magnetic resonance spectral analysis. Thus, 7-α-glucoside, 7-α-isomaltoside, and 4-α-glucoside of validamine and 7-α-glucoside, 7-α-isomaltoside, 4-α-glucoside, and 4-α-isomaltoside of valienamine were obtained from maltose and validamine or valienamine using α-glucosidase. 7-β-Glucoside, 2-β-glucoside, and 4-β-glucoside of validamine or valienamine were obtained from cellobiose and validamine or valienamine using β-glucosidase. These derivatives were tested for α-glucosidase inhibitory activity on rat small intestinal glycosidases.
