73413-69-1

Usage

Uses

Used in Pharmaceutical Industry:
(1E)-3,4,5,6-tetra-O-acetyl-1,2,7-trideoxy-1-(6-oxo-3,6-dihydro-2H-pyran-2-yl)hept-1-enitol is used as a potential pharmaceutical compound for its intricate structure and possible biological activity. The molecule's unique composition may offer novel therapeutic avenues, although further research is necessary to fully explore its properties and applications.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (1E)-3,4,5,6-tetra-O-acetyl-1,2,7-trideoxy-1-(6-oxo-3,6-dihydro-2H-pyran-2-yl)hept-1-enitol serves as a candidate for the development of new drugs. Its complex structure may allow for the targeting of specific biological pathways or the interaction with certain receptors, which could be beneficial in treating various diseases. However, additional studies are required to determine its exact role and efficacy in medicinal chemistry.

Upstream product

• 116180-60-0 ((4R,5S)-2,2-dimethyl-5-((4S,5S)-2,2,5-trimethyl-1,3-dioxolan-4-yl)-1,3-dioxolan-4-yl)methanol 
• 116096-54-9 (4S,5R)-2,2-dimethyl-5-((4S,5S)-2,2,5-trimethyl-1,3-dioxolan-4-yl)-1,3-dioxolane-4-carbaldehyde 
• 688753-66-4 (2E,4R,5S,6S,7S)-5-(tert-butyldimethylsilyloxy)-7-(tert-butyldiphenylsilyloxy)-4,6-bis(methoxymethoxy)-oct-2-en-1-ol 
• 108-24-7 acetic anhydride 
• 111860-13-0 (S)-6-[(Z)-2-((4R,5S,4'R,5'R)-2,2,2',2',5'-Pentamethyl-[4,4']bi[[1,3]dioxolanyl]-5-yl)-vinyl]-5,6-dihydro-pyran-2-one 
• 111955-41-0 (S)-6-[(E)-2-((4R,5S,4'R,5'R)-2,2,2',2',5'-Pentamethyl-[4,4']bi[[1,3]dioxolanyl]-5-yl)-vinyl]-5,6-dihydro-pyran-2-one 
• 85325-93-5 1,2-anhydro-3,4:5,6-di-O-isopropylidene-D-glucitol 
• 13035-59-1 (S)-1-((4R,4'R,5R)-2,2,2',2'-tetramethyl-4,4'-bi(1,3-dioxolan)-5-yl)prop-2-en-1-ol 
• 1384962-76-8 tert-butyldiphenyl ((S)-1-((4R,4'R,5S)-2,2,2',2'-tetramethyl-4,4'-bi(1,3-dioxolan)-5-yl)allyloxy)silane 
• 1384962-74-6 (R)-1-((4R,5S)-5-((S)-1-(tert-butyldiphenylsilyloxy)allyl)-2,2-dimethyl-1,3-dioxolan-4-yl)ethane-1,2-diol 
• 1384962-77-9 C₃₃H₄₂O₇SSi 
• 1384962-73-5 (S)-6-vinyl-5,6-dihydro-2H-pyran-2-one 
• 1384962-72-4 (2R,3R,4R,5S)-hept-6-en-2,3,4,5-tetrayl tetraacetate 
• 1384962-75-7 C₁₆H₂₀O₄ 

Relevant academic research and scientific papers

Stereoselective Total Synthesis of (+)-Anamarine and 8- epi -(-)-Anamarine from D-Mannitol

Stereoselective total synthesis of (+)-anamarine and the first synthesis of 8-epi-(-)-anamarine, its nonnatural diastereomer, were achieved from readily available d-mannitol. The key reactions involved were asymmetric dihydroxylation, cross-metathesis and ring-closing metathesis reactions. The approach is adoptable advantageously for the diversity-oriented synthesis of several related classes of natural products.

Stereoselective total synthesis of (+)-boronolide, (+)-anamarine, 8-epi-spicegerolide

A stereoselective total synthesis of the naturally occurring cytotoxic lactones (+)-boronolide, (+)-anamarine, and 8-epi-spicigerolide is described. d-Xylose has been used as a chiral source to construct the four contiguous oxygenated stereogenic centers

Total synthesis of (+)-anamarine

An enantiospecific total synthesis of polyhydroxy δ-pyrone natural product (+)-anamarine is accomplished. The main features of the synthesis include the stereoselective reduction of the ketone obtained by the desymmetrization of the bis-dimethyl amide of

Total synthesis of (+)-anamarine

Total synthesis of (+)-anamarine a polyoxygenated δ-pyranone natural product was accomplished via cross-metathesis protocol starting from 3-butene-1-ol and glycidol. Other key features of this synthetic strategy include use of Sharpless asymmetric epoxida

An efficient total synthesis of (-)-anamarine

An efficient synthesis of (-)-anamarine is described using d(+)-mannitol and (R)-epichlorohydrin. The synthesis is achieved starting from easily accessible d(+)-mannitol using a selective benzoylation, regioselective epoxide ring opening, a selective acetonide deprotection, tosylation and cross metathesis reaction.

Total synthesis of (-)-anamarine

Total synthesis of polyhydroxy δ-pyranone natural product (-)-anamarine is accomplished from d-(-)-tartaric acid. The main feature of the synthesis is the utility of hitherto unexplored β-keto phosphonate derived from tartaric acid amide and further elaboration involving stereoselective reduction.

Stereoselective total synthesis of (+)-anamarine via cross-metathesis protocol

A convergent stereoselective total synthesis of (+)-anamarine via cross-metathesis (CM) protocol starting from 2-butyn-1,4-diol and vinyl lactone is reported. Other key features of the strategy include the use of Sharpless asymmetric epoxidation, Sharples

De novo asymmetric synthesis of anamarine and its analogues

The enantioselective synthesis of anamarine has been achieved in 21 steps. The route relies on enantio- and regioselective Sharpless dihydroxylation of dienoate ester and zinc borohydride reduction to establish the C-8-C-11 stereochemistry. A diastereosel

Stereoselective synthesis of anamarine

A stereoselective synthesis of the naturally occurring, α,β-unsaturated lactone anamarine is described. The key step was a highly stereoselective aldol reaction of a protected erythrulose derivative with a chiral aldehyde. Another relevant step was an asy

THE SYNTHESIS OF (-)-ANAMARINE

The enantiospecific total synthesis of (-)-anamarine, starting from D-glucose, has been carried out.