73415-55-1Relevant academic research and scientific papers
A highly efficient Pd-C catalytic hydrogenation of pyridine nucleus under mild conditions
Cheng, Chuanjie,Xu, Jimin,Zhu, Rui,Xing, Lixin,Wang, Xinyan,Hu, Yuefei
supporting information; scheme or table, p. 8538 - 8541 (2009/12/24)
A synergistic Pd-C catalytic hydrogenation of 4-pyridinecarboxamides straightforward to 4-piperidinecarboxamide hydrochlorides was developed in the presence of ClCH2CHCl2. It provided a novel strategy for highly efficient hydrogenati
2,4-Diamino-6,7-dimethoxyquinazolines. 2. 2-(4-Carbamoylpiperidino) Derivatives as α1-Adrenoceptor Antagonists and Antihypertensive Agents
Alabaster, Valerie A.,Campbell, Simon F.,Danilewicz, John C.,Greengrass, Colin W.,Plews, Rhona M.
, p. 999 - 1003 (2007/10/02)
A series of 4-amino-2-(4-carbamoylpiperidino)-6,7-dimethoxyquinazolines (2) were synthesized and evaluated for α-adrenoceptor affinity and antihypertensive activity.These compounds displayed high binding affinity (Ki, 10-9-10-10
4-Amino-2-piperidino-quinazolines
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, (2008/06/13)
Regulators of the cardiovascular system and, in particular, in the treatment of hypertension having the formula STR1 wherein R is lower alkyl; X, is a 3- or 4-position substituent and is --(CH2)n CONR1 R2, --O(C
