73415-61-9

Usage

Uses

Used in Organic Synthesis:
PIPERIDINE-4-CARBOXYLIC ACID (2-METHOXY-ETHYL)-AMIDE is used as a building block in organic synthesis for the creation of various organic compounds. Its unique structure allows for the formation of different chemical entities, making it a versatile component in the synthesis of complex organic molecules.
Used in Pharmaceutical Research:
In the pharmaceutical industry, PIPERIDINE-4-CARBOXYLIC ACID (2-METHOXY-ETHYL)-AMIDE is used as an intermediate in the production of various pharmaceuticals. Its presence in the synthesis process can contribute to the development of new drugs with potential therapeutic benefits.
Used in Medicinal Chemistry:
PIPERIDINE-4-CARBOXYLIC ACID (2-METHOXY-ETHYL)-AMIDE is also used in medicinal chemistry for studying its biological activity and potential therapeutic properties. Researchers may investigate its interactions with biological targets and evaluate its efficacy in treating specific diseases or conditions.

Upstream product

• 73415-78-8 N-(2-methoxyethyl)-1-<(phenylmethoxy)carbonyl>-4-piperidinecarboxamide 
• 10314-99-5 benzyl 4-(chlorocarbonyl)piperidine-1-carboxylate 
• 109-85-3 2-methoxyethylamine 

Relevant academic research and scientific papers

SUBSTITUTED FUSED TRICYCLIC COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF

The present invention relates to substituted fused tricyclic compounds of formula (I) or (Ia), their tautomers, polymorphs, stereoisomers, prodrugs, solvates, co-crystals, pharmaceutically acceptable salts, pharmaceutical compositions containing them and methods of treating conditions and diseases that are mediated by JAK activity. The compounds of the present invention are useful in the treatment, prevention or suppression of diseases and disorders mediated by JAK activity. Such conditions include, but not limited to, arthritis, Alzheimer's disease, autoimmune thyroid disorders, cancer, diabetes, leukemia, T-cell prolymphocytic leukemia, lymphoma, myleoproliferation disorders, lupus, multiple myeloma, multiple sclerosis, osteoarthritis, sepsis, psoriatic arthritis, prostate cancer, T-cell autoimmune disease, inflammatory diseases, chronic and acute allograft transplant rejection, bone marrow transplant, stroke, asthma, chronic obstructive pulmonary disease, allergy, bronchitis, viral diseases, or Type I diabetes, complications from diabetes, rheumatoid arthritis, asthma, Crohn's disease, dry eye, uveitis, inflammatory bowel disease, organ transplant rejection, psoriasis and ulcerative colitis. The present disclosure also relates to process for the preparation of such compounds, and to pharmaceutical compositions containing them.

2,4-Diamino-6,7-dimethoxyquinazolines. 2. 2-(4-Carbamoylpiperidino) Derivatives as α1-Adrenoceptor Antagonists and Antihypertensive Agents

A series of 4-amino-2-(4-carbamoylpiperidino)-6,7-dimethoxyquinazolines (2) were synthesized and evaluated for α-adrenoceptor affinity and antihypertensive activity.These compounds displayed high binding affinity (Ki, 10-9-10-10

4-Amino-2-piperidino-quinazolines

Regulators of the cardiovascular system and, in particular, in the treatment of hypertension having the formula STR1 wherein R is lower alkyl; X, is a 3- or 4-position substituent and is --(CH2)n CONR1 R2, --O(C