73453-38-0

Basic information

• Product Name: Benzenamine, 4-[(2,6-diphenyl-4H-thiopyran-4-ylidene)methyl]-N,N-dimethyl-
• CAS NO: 73453-38-0
• Molecular Formula: C26H23NS
• Molecular Weight: 381.541
• Mol File: 73453-38-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzenamine, 4-[(2,6-diphenyl-4H-thiopyran-4-ylidene)methyl]-N,N-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, 4-[(2,6-diphenyl-4H-thiopyran-4-ylidene)methyl]-N,N-dimethyl-(73453-38-0)
• EPA Substance Registry System: Benzenamine, 4-[(2,6-diphenyl-4H-thiopyran-4-ylidene)methyl]-N,N-dimethyl-(73453-38-0)

Safety Data

• Hazardous Substances Data: 73453-38-0(Hazardous Substances Data)

Upstream product

• 62310-06-9 Diethyl (2,6-diphenyl-4-hydroxy-4H-tetrahydrothiopyran-4-yl)phosphonate 
• 37014-01-0 4-oxo-2,6-diphenyl-thiane 
• 71750-06-6 2,6-diphenyl-2H-thiopyran 
• 57094-07-2 2,6-diphenyl-4H-thiopyran 
• 73453-39-1 Diethyl (2,6-diphenyl-2H-thiopyran-4-yl)phosphonate 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 80160-61-8 2,6-diphenyl-4-(trimethylsilyl)-4H-thiopyran 
• 13586-29-3 2,6-diphenylthiopyrilium perchlorate 
• 55221-37-9 2,6-diphenyl-4-hydroxy-4H-tetrahydrothiopyran 

Relevant articles and documents

Synthesis and Reactions of 2,6-Diphenyl-4-(trimethylsilyl)-4H-thiopyran

The title compound 3 was synthesized by trimethylsilyl chloride quenching of 2,6-diphenyl-4-lithio-4H-thiopyran (7), which was obtained by direct lithiation (n-BuLi) of either the 4H-thiopyran 10 or the 2H isomer 6.Compound 6 was readily prepared in one step from the reaction of 2,6-diphenyl-4-hydroxy-4H-thiopyran (5) with NCS in 74percent yield.Compound 3 was metalated to give 12 in 80-85percent yield by using a combination of n-BuLi and t-BuOK in THF at an internal temperature slightly below -20 deg C.The successful reaction of 12 with a variety of ketones and aldehydes provides an alternative synthesis of the Δ4-2,6-diphenyl-4H-thiopyrans 16.The scope and limitation of this Peterson-type reaction of 12 is compared with those of the corresponding Wittig-Horner reagent 2.