73481-50-2

Upstream product

• 140-29-4 phenylacetonitrile 
• 80-62-6 methacrylic acid methyl ester 

Downstream Products

• 423754-67-0 5-(4-methoxy-phenyl)-4-methyl-5-oxo-2-phenyl-pentanoic acid 
• 423754-87-4 methyl 5-(4-methoxyphenyl)-4-methyl-5-oxo-2-phenylpentanoate 
• 423754-62-5 2-methyl-4-phenylpentanedioic anhydride 
• 339550-17-3 2-methyl-4-phenylpentanedioic acid 

Relevant academic research and scientific papers

Studies in the Friedel-Crafts reaction: Part VI - Synthesis and intra-, and intermolecular Friedel-Crafts reaction of 2-methyl-4-phenylpentanedioic anhydride

2-Methyl-4-phenylpentanedioic acid 4 is prepared by the Michael reaction of methyl methacrylate with ethyl/methyl phenylacetate or benzyl cyanide followed by the hydrolysis of the adduct. The reaction has been studied using different bases. 4 is converted