73497-66-2Relevant articles and documents
Asymmetric Synthesis of α-Substituted Amino Acids and Amines by Carbon-Carbon Bond Formation in Position α to the Nitrogen
Kolb, Michael,Barth, Jacqueline
, p. 1668 - 1688 (2007/10/02)
The asymmetric synthesis of α-substituted α-amino acids and propargylamines is described.As chiral auxiliary we used (S)-(-)-1-dimethoxymethyl-2-methoxymethylpyrrolidine (SDMP, 1).Treatment of the amino acids or amines with SDMP 1 afforded the correspondi