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4-Hydroxy-benzaldehyde 4-o-tolyl-thiosemicarbazone is a chemical compound with the molecular formula C15H14N2OS. It is derived from the condensation of 4-hydroxy-benzaldehyde with 4-o-tolyl-thiosemicarbazone, resulting in a Schiff base. 4-hydroxy-benzaldehyde 4-o-tolyl-thiosemicarbazone is known for its potential applications in coordination chemistry, particularly as a ligand for metal complexes. It exhibits interesting properties such as fluorescence and can be used in the development of sensors and imaging agents. The compound's structure features a hydroxyl group attached to a benzene ring, an aldehyde group, and a thiosemicarbazone moiety, which contributes to its reactivity and coordination capabilities with metal ions.

735-89-7

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735-89-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 735-89-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,3 and 5 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 735-89:
(5*7)+(4*3)+(3*5)+(2*8)+(1*9)=87
87 % 10 = 7
So 735-89-7 is a valid CAS Registry Number.

735-89-7Relevant academic research and scientific papers

One-pot two-step facile synthesis of 2,3,4,5-tetra substituted dihydrooxazoles and their antimicrobial activity

Tiwari, Shailendra,Pathak, Poonam,Pratap Singh, Kamal,Sagar, Ram

supporting information, p. 3802 - 3805 (2017/07/27)

New 2,3,4,5-tetra substituted dihydrooxazoles derivatives were efficiently synthesized starting from benzaldehyde, aryl thiosemicarbazide and benzoin using designed synthetic route. Newly synthesized 2,3,4,5-tetra substituted dihydrooxazole derivatives we

Synthesis and Ribonucleotide reductase inhibitory activity of thiosemicarbazones

Krishnan, Kesavan,Prathiba, Kumari,Jayaprakash, Venkatesan,Basu, Arijit,Mishra, Nibha,Zhou, Bingsen,Hu, Shuya,Yen, Yun

supporting information; experimental part, p. 6248 - 6250 (2009/08/07)

Ribonucleotide reductase (RR) is an important therapeutic target for anticancer drugs. The structure of human RR features a 1:1 complex of two homodimeric subunits, hRRM1 and hRRM2. Prokaryotically expressed and highly purified recombinant human RR subunits, hRRM1 and hRRM2, were used for holoenzyme-based [3H]CDP reduction in vitro assay. Ten new thiosemicarbazones (7-16) were synthesized and screened for their RR inhibitory activity. Two thiosemicarbazones derived from p-hydroxy benzaldehyde (9 and 10) were found to be active but less potent than the standard, Hydroxyurea (HU). Guided by the activity of compounds 9 and 10, 11 new thiosemicarbazones (17-27) derived from p-hydroxy benzaldehyde were prepared and screened for their RR inhibitory activity. All the 11 compounds were more potent than HU.

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