73516-68-4

Upstream product

• 17669-23-7 3-phenyl-cis-4,5-dimethyl-Δ²-isoxazoline 
• 42563-57-5 β-(2R,3R,4R)/(2S,3S,4S)-4-Amino-3-methyl-4-phenyl-2-butanol 

Relevant academic research and scientific papers

Syntheses via Isoxazolines, 6. - Asymmetric Induction in the Reduction of 2-Isoxazolines to Yield γ-Amino Alcohols with Two or Three Vicinal Stereocentres

The substituted 3-aminopropanols 3 and 5 with two or three adjacent chiral centres are prepared from alkenes and nitrile oxides via LiAlH4 reduction of intermediate isoxazolines 2 and 4, respectively, in a regio- and stereoselective mode. 4-Alkyl groups g