735231-40-0

Basic information

• Product Name: C₁₇H₂₁NO
• Synonyms: C₁₇H₂₁NO
• CAS NO: 735231-40-0
• Molecular Weight: 255.36
• Mol File: 735231-40-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₇H₂₁NO(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₇H₂₁NO(735231-40-0)
• EPA Substance Registry System: C₁₇H₂₁NO(735231-40-0)

Safety Data

• Hazardous Substances Data: 735231-40-0(Hazardous Substances Data)

Upstream product

• 770-39-8 4-methoxyphenylacetone 
• 3886-69-9 (R)-1-phenyl-ethyl-amine 

Downstream Products

• 1518-89-4 (-)-Hydroxyamphetamine 
• 1693-66-9 (+)-Hydroxyamphetamine 

Relevant articles and documents

Improved synthetic method of (R)-1-aryl-2-propylamine

The invention provides an improved synthetic method of (R)-1-aryl-2-propylamine. The improved synthetic method comprises the following steps of: adopting 1-arylacetone as a raw material, adding (R)-1-phenylethylamine, carrying out reductive amination reaction with hydrogen under a common action of a Lewis acid additive and a transitional metal hydrogenation catalyst; carrying out Pd/C catalytic hydrogenation on an obtained intermediate to remove phenethyl on nitrogen and thus obtaining (R)-1-aryl-2-propylamine. The improved synthetic method provided by the invention has the beneficial effectsthat the operation is simple, the adopted Lewis acid additive is low in cost and easy in obtaining, the yield and the enantioselectivity of a product are high, and the application value for industrialsynthesis of (R)-1-aryl-2-propylamine is very high.