735269-41-7Relevant academic research and scientific papers
Ac2O-Mediated Dearylacetylative Dimerization of 2-Arylacetyl-1-naphthols: Synthesis of Naphtho[1,2-b]furan-3-ones
Chang, Meng-Yang,Chen, Kuan-Ting,Chen, Shin-Mei,Hsiao, Yu-Ting
, p. 3605 - 3616 (2020/03/23)
A novel and efficient route for the synthesis of 2-Aryl-2-naphthyl naphtho[1,2-b]furan-3-ones is described via NaH/Ac2O-mediated dearylacetylative dimerization of 2-Arylacetyl-1-naphthols in refluxing THF under open-flask conditions. A plausibl
An efficient process for the large-scale synthesis of a 2,3,6-trisubstituted indole
Alorati, Anthony D.,Gibb, Andrew D.,Mullens, Peter R.,Stewart, Gavin W.
, p. 1947 - 1952 (2013/03/14)
The efficient synthesis of a key trisubstituted indole intermediate 1 is described. The synthetic route required the use of an aryl Grignard reagent which was not commercially available, and the large-scale formation of this fragment and the thermal evalu
α-Arylation of aryl ketones: Expanding the scope of the Truce-Smiles rearrangement
Snape, Timothy J.
experimental part, p. 2689 - 2691 (2009/04/11)
The Truce-Smiles rearrangement has been applied to the synthesis of substituted a-aryl aryl ketones and the synthetic utility of the products has been demonstrated by the conversion of one of them to the substituted indole 2-(1H-indol-2-yl)phenol.
A homologous enolate Truce-Smiles rearrangement
Mitchell, Lorna H.,Barvian, Nicole C.
, p. 5669 - 5671 (2007/10/03)
During preparation of a series of diphenyl ethers it was observed that displacement of an activated aryl fluoride with ortho-hydroxyacetophenone afforded a product that was C-arylated adjacent to the ketone. Evidence suggested this product was formed by Smiles rearrangement of an O-arylated intermediate.
