735279-68-2Relevant academic research and scientific papers
Studies on the synthesis of the inostamycin natural products: A reductive aldol/reductive claisen approach to the C10-C24 ketone fragment
Fuller, Nathan O.,Morken, James P.
, p. 4867 - 4869 (2007/10/03)
(Chemical Equation Presented) An approach to the C10-C 24 ketone fragment of the inostamycin family of polyether antibiotics is described. The synthetic strategy utilizes an asymmetric Rh-catalyzed reductive aldol reaction and a ster
Investigation of the Rh-catalyzed asymmetric reductive aldol reaction. Expanded scope based on reaction analysis
Russell, Albert E.,Fuller, Nathan O.,Taylor, Steven J.,Aurriset, Pauline,Morken, James P.
, p. 2309 - 2312 (2007/10/03)
(Equation Presented) A series of experiments are described that suggest that the Rh-catalyzed reductive aldol reaction proceeds by addition of a Rh(I) hydride, generated in situ, to the reacting acrylate followed by a stereochemistry-controlling aldol add
