735291-35-7Relevant academic research and scientific papers
Cul catalyzed N-arylation of amide as a key step for the preparation of 3-aryl β-carbolin-1-ones
Wang, Shaozhong,Sun, Jianwei,Yu, Gang,Hu, Xiaoyi,Liu, Jun O.,Hu, Yuefei
, p. 1573 - 1574 (2004)
An expedient synthetic route for 3-aryl β-carbolin-1-ones was developed starting from ethyl acetamidocyanoacetate and chalcone derivatives. The five- and six-membered nitrogen-containing rings in the β-carbolin-1- ones were elaborated efficiently by an in
3-Aryl β-carbolin-1-ones as a new class of potent inhibitors of tumor cell proliferation: Synthesis and biological evaluation
Wang, Shaozhong,Dong, Yanmei,Wang, Xinyan,Hu, Xiaoyi,Liu, Jun O.,Hu, Yuefei
, p. 911 - 916 (2007/10/03)
A novel three-step synthesis of 3-aryl β-carbolin-1-ones from non-indole starting materials has been developed. The two nitrogen atoms in β-carbolin-1-one were introduced efficiently by Michael addition of ethyl acetamidocyanoacetate to chalcone. The desi
