735291-49-3

Upstream product

• 90877-70-6 ethyl 2-acetamido-2-cyanoacetate 
• 58344-66-4 (E)-3-(6-bromobenzo[d][1,3]dioxol-5-yl)-1-phenylprop-2-en-1-one 
• 735291-31-3 2-acetylamino-2-cyano-3-(2-bromo-4,5-methylenedioxyphenyl)-5-oxo-5-phenylpentanoic acid ethyl ester 

Relevant academic research and scientific papers

3-Aryl β-carbolin-1-ones as a new class of potent inhibitors of tumor cell proliferation: Synthesis and biological evaluation

A novel three-step synthesis of 3-aryl β-carbolin-1-ones from non-indole starting materials has been developed. The two nitrogen atoms in β-carbolin-1-one were introduced efficiently by Michael addition of ethyl acetamidocyanoacetate to chalcone. The desi

Cul catalyzed N-arylation of amide as a key step for the preparation of 3-aryl β-carbolin-1-ones

An expedient synthetic route for 3-aryl β-carbolin-1-ones was developed starting from ethyl acetamidocyanoacetate and chalcone derivatives. The five- and six-membered nitrogen-containing rings in the β-carbolin-1- ones were elaborated efficiently by an in