73565-87-4 Usage
Uses
Used in Pharmaceutical Industry:
CORTISOL-9,11,12,12-D4 is used as an internal standard for the quantification of hydrocortisone/cortisol levels in biological samples. This is crucial for the development and quality control of pharmaceutical products containing hydrocortisone or cortisol, ensuring accurate dosing and therapeutic efficacy.
Used in Clinical Diagnostics:
CORTISOL-9,11,12,12-D4 is used as a reference compound in clinical diagnostic tests to measure cortisol levels in patients. This helps in diagnosing and monitoring various conditions such as stress-related disorders, major depressive disorder, certain forms of hypertension, and Parkinson's disease, where cortisol levels may be elevated.
Used in Research:
CORTISOL-9,11,12,12-D4 is used as a research tool in scientific studies to investigate the role of cortisol in various physiological processes and disease states. It aids in understanding the complex interactions of cortisol with other hormones and signaling pathways, contributing to a better understanding of the hypothalamic-pituitary-adrenal (HPA) axis and its role in stress response.
Used in Anti-inflammatory Applications:
As a synthetic analogue of cortisol, CORTISOL-9,11,12,12-D4 can be used in research and development of anti-inflammatory drugs. Cortisol, also known as hydrocortisone when used therapeutically, is a potent anti-inflammatory hormone that suppresses the immune system and reduces inflammation. The deuterated analogue can help in the design and optimization of new anti-inflammatory agents with improved efficacy and reduced side effects.
Used in Metabolic Studies:
CORTISOL-9,11,12,12-D4 can be employed in metabolic studies to investigate the role of cortisol in regulating glucose metabolism, fat metabolism, and protein metabolism. Cortisol is known to increase blood sugar levels through gluconeogenesis and plays a crucial role in the body's response to stress. The use of CORTISOL-9,11,12,12-D4 in these studies can provide valuable insights into the mechanisms of cortisol action and its impact on overall metabolic health.
Check Digit Verification of cas no
The CAS Registry Mumber 73565-87-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,3,5,6 and 5 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 73565-87:
(7*7)+(6*3)+(5*5)+(4*6)+(3*5)+(2*8)+(1*7)=154
154 % 10 = 4
So 73565-87-4 is a valid CAS Registry Number.
InChI:InChI=1/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15?,16-,18?,19-,20-,21?/m0/s1/i10D2,16D,18D