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(7S)-2-hydroxy-1,3,10-trimethoxy-7-(methylamino)-6,7-dihydrobenzo[a]heptalen-9(5H)-one is a complex organic compound with a molecular formula of C18H23NO5. It is a derivative of benzo[a]heptalen, a type of polycyclic aromatic hydrocarbon, and features a hydroxyl group at the 2-position, three methoxy groups at the 1, 3, and 10 positions, a methylamino group at the 7-position, and a 6,7-dihydro structure. (7S)-2-hydroxy-1,3,10-trimethoxy-7-(methylamino)-6,7-dihydrobenzo[a]heptalen-9(5H)-one is characterized by its unique stereochemistry, with the 7-position being in the S-configuration. It is likely to have specific applications in the field of organic chemistry, potentially as an intermediate in the synthesis of pharmaceuticals or other complex molecules, due to its diverse functional groups and structural features.

7359-91-3

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7359-91-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 7359-91-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,3,5 and 9 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 7359-91:
(6*7)+(5*3)+(4*5)+(3*9)+(2*9)+(1*1)=123
123 % 10 = 3
So 7359-91-3 is a valid CAS Registry Number.

7359-91-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name (7S)-2-hydroxy-1,3,10-trimethoxy-7-(methylamino)-6,7-dihydro-5H-benzo[a]heptalen-9-one

1.2 Other means of identification

Product number -
Other names (S)-6,7-Dihydro-2-hydroxy-1,3,10-trimethoxy-7-(methylamino)benzo(a)heptalen-9(5H)-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:7359-91-3 SDS

7359-91-3Upstream product

7359-91-3Relevant academic research and scientific papers

Enantioselective total synthesis of (-)-colchicine, (+)-demecolcinone and metacolchicine: Determination of the absolute configurations of the latter two alkaloids

Chen, Bo,Liu, Xin,Hu, Ya-Jian,Zhang, Dong-Mei,Deng, Lijuan,Lu, Jieyu,Min, Long,Ye, Wen-Cai,Li, Chuang-Chuang

, p. 4961 - 4966 (2017/07/10)

Here, we describe a concise, enantioselective, and scalable synthesis of (-)-colchicine (9.2% overall yield, >99% ee). Moreover, we have also achieved the first syntheses of (+)-demecolcinone and metacolchicine, and determined their absolute configurations. The challenging tricyclic 6-7-7 core of colchicinoids was efficiently introduced using an intramolecular oxidopyrylium-mediated [5 + 2] cycloaddition reaction. Notably, the synthesized colchicinoid 23 exhibited potent inhibitory activity toward the cell growth of human cancer cell lines (IC50 = ～3.0 nM), and greater inhibitory activity towards microtubule assembly than colchicine, making it a promising lead in the search for novel anticancer agents.

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