736-42-5Relevant academic research and scientific papers
Microwave-mediated selective monotetrahydropyranylation of symmetrical diols catalyzed by iodine
Deka,Sarma
, p. 1947 - 1948 (2007/10/03)
Selective protection of one hydroxyl group as its tetrahydropyranyl ether in 1, n-symmetrical diol is achieved by iodine-catalyzed reaction of the diol with dihydropyranyl ether under microwave irradiation.
Selective monotetrahydropyranylation of symmetrical diols catalyzed by ion-exchange resins
Nishiguchi, Takeshi,Fujisaki, Shizuo,Kuroda, Masahumi,Kajisaki, Kohtaro,Saitoh, Masahiko
, p. 8183 - 8187 (2007/10/03)
Primary and secondary symmetrical diols with 2-10 carbon atoms gave selectively monotetrahydropyranyl ethers in the reaction catalyzed by wet sulfonic acid-type ion-exchange resins in 3,4-dihydro-2H-pyran (DHP)/toluene or DHP/hexane. The yields of the monoethers were higher than 80% while those of the corresponding diethers were lower than 5%. In these reactions the rate of the formation of the diethers did not increase much even after most of the diols had been consumed. In the reaction of 1,10-decanediol in DHP/hexane, the yields of the monoether were increased by the addition of DMF or DMSO. Each diol was found to have a particular DHP/hydrocarbon ratio that gave the highest selectivity for the monoether. Generally, the larger the number of carbon atoms of the diols, the smaller the ratio of DHP in the solvents to give high selectivity for the monoether. This method of the selective etherification is quite simple and practical.
Highly Selective Monotetrahydropyranylation of Symmetrical Diols Catalysed by a Strongly Acidic Ion-exchange Resin
Nishiguchi, Takeshi,Kuroda, Masahumi,Saitoh, Masahiko,Nishida, Akiko,Fujisaki, Shizuo
, p. 2491 - 2492 (2007/10/03)
Several primary and secondary symmetrical diols, ranging from propane-1,3-diol to decane-1,10-diol, are selectively monoprotected by monotetrahydropyranyl ether formation catalysed by a strongly acidic ion-exchange resin (Dowex 50x x 2, 50-100 mesh) in a 3,4-dihydro-2H-pyran-hydrocarbon mixture.
Highly Selective Monoetherification of Symmetrical Diols Catalysed by Metallic Sulfate Supported on Silica Gel
Nishiguchi, Takeshi,Kawamine, Katsumi,Ohtsuka, Tomoko
, p. 153 - 156 (2007/10/02)
Several symmetrical primary and secondary diols from C2 to C16 have been protected in high selectivity by tetrahydropyranyl ether formation catalysed by metallic sulfates supported on silical gel.This selective etherification is simple and practical.The s
