736115-65-4Relevant academic research and scientific papers
Enantioselektive Synthese von Allyl-, Propargyl- und 4-En-2-inyl-aminen durch 1,2-Addition von Organocer-Reagenzien an chirale Aldimine
Enders, Dieter,Schankat, Juergen
, p. 970 - 992 (2007/10/02)
(E)- and (Z)-Allyl-, propargyl, and 4-en-2-ynyl-amines 5 and 14, useful bifunctional building blocks and of pharmaceutical interest, are synthesized in high enantiomeric purity (e.e. >/= 97 percent).Key step is the diastereoselective 1,2-addition (d.e. 86
Enantioselective Synthesis of Allyl- and Propargylamines via Nucleophilic 1,2-Addition to Chiral Aldimines
Enders, Dieter,Schankat, Juergen
, p. 402 - 406 (2007/10/02)
The asymmetric synthesis of allylamines and propargylamines 5 in high enantiomeric purity (e.e >/= 97percent) is described.Key step is the 1,2-addition of organocerium reagents to chiral α,β-unsaturated aldimines 3 to produce secondary amines 4.The chiral
