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2-(piperidin-4-yl)pyrazine dihydrochloride is a chemical compound characterized by the presence of a piperidine ring and a pyrazine ring, which are significant structural components in a variety of pharmaceuticals and bioactive molecules. 2-(piperidin-4-yl)pyrazine dihydrochloride is widely utilized in organic and medicinal chemistry research as a fundamental building block for the synthesis of novel compounds with potential pharmacological properties. As a dihydrochloride salt, it exhibits enhanced stability and solubility in aqueous solutions, facilitating its use in laboratory settings. The inclusion of two chloride ions further contributes to the compound's overall stability and consistency, rendering it an invaluable asset in the development of innovative drugs and bioactive molecules.

736134-74-0

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736134-74-0 Usage

Uses

Used in Pharmaceutical Research:
2-(piperidin-4-yl)pyrazine dihydrochloride serves as a key intermediate in the synthesis of new compounds with potential therapeutic applications. Its unique structure allows for the exploration of various chemical modifications, leading to the discovery of molecules with improved pharmacological profiles.
Used in Medicinal Chemistry:
As a building block in medicinal chemistry, 2-(piperidin-4-yl)pyrazine dihydrochloride is employed for the development of compounds with specific biological activities. Its presence in the molecular structure can influence the pharmacokinetic and pharmacodynamic properties of the synthesized compounds, enhancing their efficacy and safety.
Used in Organic Chemistry:
In the realm of organic chemistry, 2-(piperidin-4-yl)pyrazine dihydrochloride is utilized as a versatile reactant in various chemical reactions. Its reactivity and stability make it suitable for the preparation of a wide range of organic compounds, including those with potential applications in materials science, agrochemistry, and other fields.
Used in Drug Development:
2-(piperidin-4-yl)pyrazine dihydrochloride plays a crucial role in drug development, where it is used as a starting material for the synthesis of new drug candidates. Its stability and solubility properties ensure that it can be easily incorporated into complex synthetic routes, leading to the production of innovative pharmaceutical agents.
Used in Bioactive Molecule Synthesis:
In the synthesis of bioactive molecules, 2-(piperidin-4-yl)pyrazine dihydrochloride is employed as a structural component that can impart specific biological activities to the resulting compounds. Its presence in the molecular framework can modulate the interactions of the synthesized molecules with biological targets, potentially leading to the development of new therapeutic agents with improved efficacy and selectivity.

Check Digit Verification of cas no

The CAS Registry Mumber 736134-74-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,3,6,1,3 and 4 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 736134-74:
(8*7)+(7*3)+(6*6)+(5*1)+(4*3)+(3*4)+(2*7)+(1*4)=160
160 % 10 = 0
So 736134-74-0 is a valid CAS Registry Number.

736134-74-0Upstream product

736134-74-0Downstream Products

736134-74-0Relevant academic research and scientific papers

Potent heteroarylpiperidine and carboxyphenylpiperidine 1-alkyl-cyclopentane carboxamide CCR2 antagonists

Pasternak, Alexander,Goble, Stephen D.,Vicario, Pasquale P.,Di Salvo, Jerry,Ayala, Julia M.,Struthers, Mary,DeMartino, Julie A.,Mills, Sander G.,Yang, Lihu

, p. 994 - 998 (2008/09/19)

This report describes replacement of the 4-(4-fluorophenyl)piperidine moiety in our CCR2 antagonists with 4-heteroaryl piperidine and 4-(carboxyphenyl)-piperidine subunits. Some of the resulting analogs retained potency in our CCR2 binding assay and had i

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