736143-84-3Relevant academic research and scientific papers
Catalytic conjunctive cross-coupling enabled by metal-induced metallate rearrangement
Zhang, Liang,Lovinger, Gabriel J.,Edelstein, Emma K.,Szymaniak, Adam A.,Chierchia, Matteo P.,Morken, James P.
, p. 70 - 74 (2016/01/09)
Transition metal catalysis plays a central role in contemporary organic synthesis. Considering the tremendously broad array of transition metal-catalyzed transformations, it is remarkable that the underlying elementary reaction steps are relatively few in
Screening on the use of Kluyveromyces marxianus CBS 6556 growing cells as enantioselective biocatalysts for ketone reductions
Vitale, Paola,Perna, Filippo Maria,Perrone, Maria Grazia,Scilimati, Antonio
experimental part, p. 1985 - 1993 (2012/03/22)
The versatility of Kluyveromyces marxianus CBS 6556 growing cells in the enantioselective reduction of ketone functionalities to the corresponding alcohols was exploited. In particular, methyl ketones were reduced to (S)-alcohols with ees of up to 96%. Longer chain alkyl ketones afforded, under the same experimental condition, (R)-alcohols with an ee of up to 84%. Interestingly, carbon-carbon double and the triple bonds can also be reduced in the presence of Kluyveromyces marxianus CBS 6556 yeast. A cyclic ketone, such as 2-tetralone, was also quantitatively reduced to its corresponding (S)-alcohol with ee = 76%.
Preparation of enantiomerically enriched flavor and fragrance components
-
, (2008/06/13)
The present invention includes a process for enantioselective preparation of a non-racemic compound, which is either usable as a fragrance or flavor component or is convertible to a fragrance or flavor component by one or more additional reaction steps. T
Chiral vinyl dioxazaborocines in synthesis: Asymmetric cuprate additions to β-boronyl acrylates and vinyl sulfones
Farthing, Christopher N.,Marsden, Stephen P.
, p. 4235 - 4238 (2007/10/03)
The first examples of the addition of organometallic reagents to electron deficient boron-substituted olefins are reported. Thus, copper catalysed addition of Grignard reagents to chiral acryloyl and vinysulfonyl dioxazaborocines, followed by oxidative re
