73619-02-0

Basic information

• Product Name: 2-<4-Benzyl-1-(4-methylphenylsulfonyl)-4-piperidinyl>-2-cyanessigsaeure-ethylester
• Synonyms: 2-<4-Benzyl-1-(4-methylphenylsulfonyl)-4-piperidinyl>-2-cyanessigsaeure-ethylester
• CAS NO: 73619-02-0
• Molecular Weight: 440.563
• Mol File: 73619-02-0.mol

Chemical Properties

• CAS DataBase Reference: 2-<4-Benzyl-1-(4-methylphenylsulfonyl)-4-piperidinyl>-2-cyanessigsaeure-ethylester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-<4-Benzyl-1-(4-methylphenylsulfonyl)-4-piperidinyl>-2-cyanessigsaeure-ethylester(73619-02-0)
• EPA Substance Registry System: 2-<4-Benzyl-1-(4-methylphenylsulfonyl)-4-piperidinyl>-2-cyanessigsaeure-ethylester(73619-02-0)

Safety Data

• Hazardous Substances Data: 73619-02-0(Hazardous Substances Data)

Upstream product

• 58664-74-7 2-Cyan-2-<1-(4-methylphenylsulfonyl)-4-piperidinyliden>essigsaeure-ethylester 
• 6921-34-2 benzylmagnesium chloride 
• 1589-82-8 phenylmagnesium bromide 

Relevant articles and documents

Application of the PMC protecting group in the efficient synthesis of 4,4-disubstituted piperidines

An efficient synthesis of the 4,4-disubstituted piperidine scaffold 1 was accomplished by treating the PMC N-protected α,β-unsaturated ethyl cyanoacetate 9 with various Grignard reagents (R1MgX). Subsequent heating at 19°C in a strong base prov

1,4-Addition of Grignard Compounds to α,β-Unsaturated Ethyl Cyanoacetates

1,4-Addition of several Grignard compounds and hydrogen cyanide to the α,β-unsaturated ethyl cyanoacetates 1 and 4 leading to 2a-n and 5a-d.