73638-67-2Relevant academic research and scientific papers
Regioselective methylation of 1-benzyl-Δ9, 10-octahydro-4-quinolone
Grishina,Leshcheva,Sergeev,Potapov,Vovk
, p. 589 - 593 (2007/10/02)
The methylation of 1-benzyl-Δ9,10-octahydro-4-quinolone with methyl iodide in the presence of lithium diethylamide in tetrahydrofuran is a regioselective electrophilic substitution reaction, and, depending on the reaction conditions, takes place in the 3 or 8 position of the quinolone system. Deuteration under the same conditions takes place only in the 3 position.
