73639-91-5Relevant academic research and scientific papers
Quantitative NaH catalytic hydroboration of aldimines
An, Duk Keun,Hwang, Hyonseok,Kim, Hanbi,Lee, Ji Hye
, p. 11330 - 11335 (2020/07/15)
The catalytic hydroboration of aldimines was demonstrated, with only 3 mol% NaH required for the quantitative production of secondary amines under minimal solvent conditions. In addition, chemoselective hydroboration in the presence of other reducible functional groups was achieved. DFT calculations were then used to propose a reaction mechanism for imine hydroboration. This journal is
Lithium bromide: an inexpensive and efficient catalyst for imine hydroboration with pinacolborane at room temperature
An, Duk Keun,Hwang, Hyonseok,Kim, Hanbi,Kim, Hyun Tae,Lee, Ji Hye
, p. 34421 - 34427 (2020/10/12)
An efficient protocol for the hydroboration of imines is reported. Lithium halide salts are effective catalysts to convert aldimines and ketimines to their corresponding amines. Here, we report excellent isolated yield of secondary amines (>95%) using 3 mol% lithium bromide in THF at room temperature. In addition, DFT calculations for a plausible reaction pathway are reported.
Direct Reductive Amination of Aldehydes via Environmentally Benign Bentonite-Gold Nanohybrid Catalysis
Maya,Poulose, Susanna,John, Jubi,Luxmi Varma
, p. 1177 - 1184 (2017/04/11)
An efficient, green and reliable method for the direct reductive amination of aldehydes was developed using an environmentally benign bentonite-gold nanohybrid catalyst. Use of this heterogeneous catalyst affords a variety of secondary amines in excellent yield under ambient reaction conditions in the presence of phenyldimethylsilane as mild hydride donor. The catalyst is recyclable, selective and is well applicable for the gram-scale preparation of secondary amines. (Figure presented.).
