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N-phthaloyl-Phe-SPh, also known as N-phthaloyl-L-phenylalanine-S-phenyl ester, is a synthetic chemical compound derived from the amino acid L-phenylalanine. It is formed by the reaction of L-phenylalanine with phthalic anhydride, resulting in the formation of an amide bond between the carboxyl group of L-phenylalanine and the anhydride, followed by the esterification of the newly formed carboxyl group with phenol. N-phthaloy-Phe-SPh is often used in peptide synthesis as a protecting group for the amino group of L-phenylalanine, allowing for the controlled formation of peptide bonds in the synthesis of larger peptide structures. The "N-phthaloyl" part of the name indicates the protecting group on the nitrogen atom, while "SPh" signifies the phenyl ester group on the sulfur atom.

7364-37-6

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7364-37-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 7364-37-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,3,6 and 4 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 7364-37:
(6*7)+(5*3)+(4*6)+(3*4)+(2*3)+(1*7)=106
106 % 10 = 6
So 7364-37-6 is a valid CAS Registry Number.

7364-37-6Relevant academic research and scientific papers

Decarbonylative approach to the synthesis of enamides from amino acids: Stereoselective synthesis of the (Z)-aminovinyl-d-cysteine unit of mersacidin

Garcia-Reynaga, Pablo,Carrillo, Angela K.,Vannieuwenhze, Michael S.

supporting information; experimental part, p. 1030 - 1033 (2012/04/04)

The Pd- and Ni-promoted decarbonylation of amino acid thioesters proceeds smoothly to yield enamides. The synthesis of the (S)-(Z)-AviMeCys subunit of mersacidin, an MRSA-active lantibiotic, via this approach, is described.

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