73644-95-8

Basic information

• Product Name: 3-Methyl-1,3,4,5-tetrahydrobenzo[d]azepin-2-one
• Synonyms: 3-Methyl-1,3,4,5-tetrahydrobenzo[d]azepin-2-one;2H-3-Benzazepin-2-one, 1,3,4,5-tetrahydro-3-methyl- (9CI);3-methyl-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one;2H-3-Benzazepin-2-one;5-tetrahydro-3-Methyl-
• CAS NO: 73644-95-8
• Molecular Formula: C₁₁H₁₃NO
• Molecular Weight: 175.23
• Product Categories: API intermediates
• Mol File: 73644-95-8.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-Methyl-1,3,4,5-tetrahydrobenzo[d]azepin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Methyl-1,3,4,5-tetrahydrobenzo[d]azepin-2-one(73644-95-8)
• EPA Substance Registry System: 3-Methyl-1,3,4,5-tetrahydrobenzo[d]azepin-2-one(73644-95-8)

Safety Data

• Hazardous Substances Data: 73644-95-8(Hazardous Substances Data)

Usage

General Description

3-Methyl-1,3,4,5-tetrahydrobenzo[d]azepin-2-one is a chemical compound that belongs to the class of tetrahydrobenzoazepines. It is a cyclic compound with a molecular formula of C10H11NO and a molecular weight of 161.20 g/mol. 3-Methyl-1,3,4,5-tetrahydrobenzo[d]azepin-2-one is used in organic synthesis and pharmaceutical research, and it has been studied for its potential pharmacological properties. 3-Methyl-1,3,4,5-tetrahydrobenzo[d]azepin-2-one has been investigated for its role in the development of new drugs and as a building block for the synthesis of biologically active compounds.

InChI:InChI=1S/C11H13NO/c1-12-7-6-9-4-2-3-5-10(9)8-11(12)13/h2-5H,6-8H2,1H3

Upstream product

• 13156-97-3 2-chloro-N-phenylethylpropanamide 
• 589-08-2 N-Methyl-N-phenethylamine 
• 103-63-9 1-phenyl-2-bromoethane 
• 13230-84-7 2-chloro-N-methyl-N-(2-phenylethyl)acetamide 
• 117034-52-3 9-Hydroxy-3-methyl-3-aza-spiro[5.5]undeca-7,10-dien-2-one 
• 15987-50-5 1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one 
• 74-88-4 methyl iodide 

Downstream Products

• 1428449-34-6 4,5-dihydro-3-methyl-1-(2-tolyl)-1H-benzo[d]azepin-2(3H)-one 
• 1428449-33-5 4,5-dihydro-1-(2-methoxyphenyl)-3-methyl-1H-benzo[d]azepin-2(3H)-one 
• 1428449-32-4 4,5-dihydro-1-(4-methoxyphenyl)-3-methyl-1H-benzo[d]azepin-2(3H)-one 
• 1428449-31-3 1-(3-(trifluoromethyl)phenyl)-4,5-dihydro-3-methyl-1H-benzo[d]azepin-2(3H)-one 
• 1428449-30-2 4,5-dihydro-3-methyl-1-(3-tolyl)-1H-benzo[d]azepin-2(3H)-one 
• 1428449-29-9 4,5-dihydro-1-(3-methoxyphenyl)-3-methyl-1H-benzo[d]azepin-2(3H)-one 
• 1428449-41-5 1-(1,1'-biphenyl-4-yl)-4,5-dihydro-3-methyl-1H-benzo[d]azepin-2(3H)-one 
• 1428449-40-4 1-(4-ethylphenyl)-4,5-dihydro-3-methyl-1H-benzo[d]azepin-2(3H)-one 
• 1428449-38-0 4,5-dihydro-3-methyl-1-(3,5-dimethylphenyl)-1H-benzo[d]azepin-2(3H)-one 
• 1428449-37-9 1-(4-fluorophenyl)-4,5-dihydro-3-methyl-1H-benzo[d]azepin-2(3H)-one 
• 1428449-36-8 1-(3-fluorophenyl)-4,5-dihydro-3-methyl-1H-benzo[d]azepin-2(3H)-one 
• 1428449-35-7 4,5-dihydro-3-methyl-1-(4-tolyl)-1H-benzo[d]azepin-2(3H)-one 
• 425386-58-9 (1S)-1-amino-3-methyl-1H,4H,5H-benzo[d]azaperhydroepin-2-one di-p-toluoyl-L-tartrate 

Relevant articles and documents

SUBSTITUTED PROLINAMIDES, THE PREPARATION THEREOF AND THE USE THEREOF AS PHARMACEUTICAL COMPOSITIONS

The present invention provides new substituted prolinamides of the general formula (I) in which D, L, E, G, J, M, R3, R4, R5, and R13 are defined as in claim 1, their tautomers, their enantiomers, their diastere

SYNTHESIS OF 5-HYDROXY-3-TRIFLUOROMETHYL-PYRAZOLES BY RING OPENING OF 3-TRIFLUOROACETYL-BENZOLACTAMS

New trifluoromethylated pyrazoles 5b,c,f have been prepared by condensation of 3-trifluoroacetyl benzolactams 1a,b,c and 2 with hydrazines by opening of the lactam moiety.The structure of pyrazoles was established by X-ray diffraction analysis and by comp

BENZOLACTAMS-1. ALKYLATION OF 1,2,4,5-TETRAHYDRO-3-METHYL-3H-3-BENZAZEPIN-2-ONE WITH SODIUM HYDRIDE AND ALKYL HALIDE

Alkylation of 1,2,4,5-tetrahydro-3-methyl-3H-3-benzazepin-2-one 1a with various halides and sodium hydride in tetrahydrofuran-dimethylformamide solvent system was studied.Primary halides predominantly provided the 1-mono-substituted products, such as alkyl (2a-g,p,q), allyl (2j,k), propargyl (2l) and benzyl (2m-o) derivatives, in satisfactory yields, and secondary halides resulted in lower yields (2h,i) than primary halides.In attempted dialkylations with ω,ω'-dibromoalkanes, 5- and 6-membered spiro products (4c,d) were obtained by this method.The Michael type addition reaction was also studied and it was found that acrylic acid esters gave the corresponding adducts (2p,q).