73676-86-5Relevant academic research and scientific papers
Synthesis and Biological Evaluation of 2-Styrylquinazolin-4(3H)-ones, a New Class of Antimitotic Anticancer Agents Which Inhibit Tubulin Polymerization
Jiang, J. B.,Hesson, D. P.,Dusak, B. A.,Dexter, D. L.,Kang, G. J.,Hamel, E.
, p. 1721 - 1728 (2007/10/02)
A novel series of 2-styrylquinazolin-4(3H)-ones which inhibited tubulin polymerization and the growth of L1210 murine leukemia cells was discovered.Extensive structure-activity relationship studies suggest that the entire quinazolinone structure was requi
SYNTHESIS AND STRUCTURE OF 1,1-DIOXIDES OF 3-ALLLYL(STYRYL)-4H-1,2,4-BENZOTHIADIAZINE
Fedenko, V. S.,Solomko, Z. F.,Avramenko, V. I.
, p. 735 - 739 (2007/10/02)
The reaction of o-aminobenzenesulfonamides with acids of crotonic and cinnamic acids in dioxane yielded the corresponding anilides, which were cyclized to derivatives of 1,2,4-benzothiadiazine 1,1-dioxide.The structure of the end products is discussed in connection with the possibility of tautomeric equilibrium of the 2H- and 4H-forms on the basis of the spectral data.
