73687-66-8

Upstream product

• 73687-74-8 (1S,4S)-1-acetoxy-2,2,3,3,4-pentadeuterio-4-methylcyclohexane 
• 73687-72-6 (1S,4S)-1-acetyl-2,2,3,3,4-pentadeuterio-4-methylcyclohexane 
• 73687-70-4 (1S,4S)-1-isopropenyl-2,2,3,3,4-pentadeuterio-4-methylcyclohexane 
• 5524-05-0 (-)-dihydrocarvone 
• 73687-76-0 (1S,4S)-2,2,3,3,4-pentadeuterio-4-methylcyclohexan-1-ol 
• 73687-68-0 dihydrocarvone-2,6,6-d3 

Downstream Products

• 73687-67-9 (4S)-2,2,3,3,4,6,6-heptadeuterio-4-methylcyclohexanone 

Relevant academic research and scientific papers

Optical Rotatory Dispersion Studies. 130. Additivity of Deuterium Octant Contributions in Cyclohexanone

A comparison between the circular dichroism spectra of (4S)-3,3-dideuterio-4-methylcyclohexanone (1), (3R,4R)-3-deuterio-4-tert-butylcyclohexanone (2) and (3S,4R)-3-deuterio-4-tert-butylcyclohexanone (3) leads to the conclusion that the octant contributions of deuterium in the β-equatorial and β-axial positions of the cyclohexanone ring are additive.From the temperature-dependent circular dichroism spectra of 1 an energy difference of -1.1 kcal/mol was obtained for the conformations with the 4-methyl substituent in the axial and equatorial position, respectively.