73694-37-8

Basic information

• Product Name: (2E)-1-(2,4,6-trimethoxyphenyl)-3-(2,4,5-trimethoxyphenyl)-2-propen-1-one
• CAS NO: 73694-37-8
• Molecular Weight: 388.417
• Mol File: 73694-37-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2E)-1-(2,4,6-trimethoxyphenyl)-3-(2,4,5-trimethoxyphenyl)-2-propen-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (2E)-1-(2,4,6-trimethoxyphenyl)-3-(2,4,5-trimethoxyphenyl)-2-propen-1-one(73694-37-8)
• EPA Substance Registry System: (2E)-1-(2,4,6-trimethoxyphenyl)-3-(2,4,5-trimethoxyphenyl)-2-propen-1-one(73694-37-8)

Safety Data

• Hazardous Substances Data: 73694-37-8(Hazardous Substances Data)

Upstream product

• 5273-86-9 C₁₂H₁₆O₃ 

Relevant articles and documents

Synthesis, anticancer and antioxidant activities of 2,4,5-trimethoxy chalcones and analogues from asaronaldehyde: Structure-activity relationship

2,4,5-Trimethoxy chalcones and analogues were synthesized from asaronaldehyde derived from β-asarone. These novel compounds when tested against three human tumour cell lines (MCF-7, SW-982 and HeLa) using MTT assay, revealed that chalcones possessing electron donor groups in para position to carbonyl moiety of phenyl ring A, showed better inhibitory activity (2, 3, 4, 6, 7, 10, 17). When evaluated for antioxidant activities, compound 15 exhibited better free radical scavenging property in DPPH assay while compounds 2, 3, 5, 7, 9, 10, 11, 16, and 18 showed significant NO scavenging activity. All compounds exhibited very good phenyl hydrazine induced haemolysis of erythrocytes in phenylhydrazine assay. Structure-activity relationship (SAR) study using in-silico analysis matched well with in-vitro tumour cell inhibitory activity.