73698-08-5

Basic information

• Product Name: (S)-Hydroxy-naphthalen-1-yl-phenyl-acetic acid
• Synonyms: (S)-Hydroxy-naphthalen-1-yl-phenyl-acetic acid
• CAS NO: 73698-08-5
• Molecular Weight: 278.307
• Mol File: 73698-08-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (S)-Hydroxy-naphthalen-1-yl-phenyl-acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-Hydroxy-naphthalen-1-yl-phenyl-acetic acid(73698-08-5)
• EPA Substance Registry System: (S)-Hydroxy-naphthalen-1-yl-phenyl-acetic acid(73698-08-5)

Safety Data

• Hazardous Substances Data: 73698-08-5(Hazardous Substances Data)

Upstream product

• 1361326-08-0 (2-naphthyl)-2-(1-naphthyl)-2-hydroxyphenylacetate 
• 13922-41-3 1-Naphthylboronic acid 
• 58635-82-8 (S,S)-2-benzyl-4-methoxymethyl-5-phenyl-2-oxazoline 
• 63007-15-8 trans-(4S,5S)-2-benzoyl-4-(methoxymethyl)-5-phenyl-2-oxazoline 
• 1074-12-0 phenylglyoxal hydrate 
• 115156-57-5 (2S,4aS,7R,8aR)-2-benzoyl-N-benzyl-4,4,7-trimethyl-octahydro-1,3-benzoxazine 
• 703-55-9 1-naphthylmagnesiumbromide 
• 18434-67-8 O-(naphthyl-⁽¹⁾-oxoacetyl)-(1R)-menthol 
• 73698-01-8 ((4S,5S)-4-Methoxymethyl-5-phenyl-4,5-dihydro-oxazol-2-yl)-naphthalen-1-yl-phenyl-methanol 

Relevant articles and documents

Rhodium-catalyzed, highly enantioselective 1,2-addition of aryl boronic acids to α-ketoesters and α-diketones using simple, chiral sulfur-olefin ligands

Simply the best: The title reaction has been achieved by asymmetric rhodium catalysis employing an extremely simple, chiral N-(sulfinyl)cinnamylamine ligand. A variety of highly enantioenriched, tertiary α-hydroxy carbonyl derivatives were easily accessed

Asymmetric Addition of Organometallics to Chiral Ketooxazolines. Preparation of Enantiomerically Enriched α-Hydroxy Acids

Addition of Grignard and organolithium reagents to chiral α-ketooxazolines results in α-substituted α-hydroxyoxazoline derivatives which on hydrolytic removal of the chiral auxiliary groups give rise to α-substituted α-hydroxy acids in 30-87 percent enantiomeric excess (ee).Studies on the various parameters (solvents, temperature, substituents) were undertaken to reach optimum asymmetric induction.