736991-93-8

Basic information

• Product Name: 2-(N-MORPHOLINYL)-6-FLUOROBENZALDEHYDE
• Synonyms: 2-(N-MORPHOLINYL)-6-FLUOROBENZALDEHYDE;2-Fluoro-6-morpholinobenzaldehyde
• CAS NO: 736991-93-8
• Molecular Formula: C11H12FNO2
• Molecular Weight: 209.219
• Mol File: 736991-93-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(N-MORPHOLINYL)-6-FLUOROBENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(N-MORPHOLINYL)-6-FLUOROBENZALDEHYDE(736991-93-8)
• EPA Substance Registry System: 2-(N-MORPHOLINYL)-6-FLUOROBENZALDEHYDE(736991-93-8)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 736991-93-8(Hazardous Substances Data)

Usage

General Description

2-(N-Morpholinyl)-6-fluorobenzaldehyde is a chemical compound with the molecular formula C11H11NO2F. It is a pale yellow solid that is widely used in organic synthesis and as a reagent in various chemical reactions. 2-(N-MORPHOLINYL)-6-FLUOROBENZALDEHYDE is known for its ability to form stable complexes with metal ions, making it a useful tool in coordination chemistry. Additionally, 2-(N-morpholinyl)-6-fluorobenzaldehyde has been studied for its potential biological activities, including its antimicrobial and anti-inflammatory properties. It is also utilized in the development of pharmaceuticals and agrochemicals, making it a versatile and important chemical in various industries.

Upstream product

• 110-91-8 morpholine 
• 437-81-0 2,6-difluorobenzaldehyde 

Relevant articles and documents

Catalyst-free photodecarbonylation ofortho-amino benzaldehyde

It is almost a consensus that decarbonylation of the aldehyde group (-CHO) needs to not only be mediated by transition metal catalysts, but also requires severe reaction conditions (high temperature and long reaction time). In this work, inspired by the “conformational-selectivity-based” design strategy, we broke this consensus and discovered a catalyst-free photodecarbonylation of the aldehyde group. It revealed that decarbonylation can be easily achieved with visible light irradiation by introducing a tertiary amine into theortho-position of the aldehyde group. A diverse array of tertiary amines is tolerated by our photodecarbonylation under mild conditions. Furthermore, the (QM) computations of the mechanism and the experiments on well-designed special substrates revealed that our photodecarbonylation depends on the conformational specificity of the aldehyde group and tertiary amine, and occurs through an unusual [1,4]-H shift and a subsequent [1,3]-H shift.