7370-49-2 Usage
Uses
Used in Industrial Lubricants:
CIS-13,16-DOCOSADIENOIC ACID is used as a key component in the production of industrial lubricants due to its long-chain structure and monounsaturated nature, which provide the necessary viscosity and stability for lubricating applications.
Used in Chemical Synthesis:
Erucic acid serves as a raw material for the synthesis of other compounds, highlighting its versatility in the chemical industry and contributing to the creation of a range of products.
Used in Health and Nutrition Research:
CIS-13,16-DOCOSADIENOIC ACID is used as a subject of research for its potential health effects, such as its ability to improve heart health and reduce inflammation, although further studies are needed to fully understand its benefits and risks.
Used in Pharmaceutical Development:
Although not explicitly mentioned in the provided materials, the potential health effects of erucic acid may lead to its use in the development of pharmaceuticals aimed at treating specific conditions related to heart health and inflammation, subject to further research and regulatory approval.
Check Digit Verification of cas no
The CAS Registry Mumber 7370-49-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,3,7 and 0 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 7370-49:
(6*7)+(5*3)+(4*7)+(3*0)+(2*4)+(1*9)=102
102 % 10 = 2
So 7370-49-2 is a valid CAS Registry Number.
InChI:InChI=1/C22H40O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24/h6-7,9-10H,2-5,8,11-21H2,1H3,(H,23,24)/b7-6+,10-9+
7370-49-2Relevant academic research and scientific papers
Elongation of the Hydrophobic Chain as a Molecular Switch: Discovery of Capsaicin Derivatives and Endogenous Lipids as Potent Transient Receptor Potential Vanilloid Channel 2 Antagonists
Schiano Moriello, Aniello,López Chinarro, Silvia,Novo Fernández, Olalla,Eras, Jordi,Amodeo, Pietro,Canela-Garayoa, Ramon,Vitale, Rosa Maria,Di Marzo, Vincenzo,De Petrocellis, Luciano
, p. 8255 - 8281 (2018/09/25)
The transient receptor potential vanilloid type-2 (TRPV2) protein is a nonselective Ca2+ permeable channel member of the TRPV subfamily, still considered an orphan TRP channel due to the scarcity of available selective and potent pharmacological tools and endogenous modulators. Here we describe the discovery of novel synthetic long-chain capsaicin derivatives as potent TRPV2 antagonists in comparison to the totally inactive capsaicin, the role of their hydrophobic chain, and how the structure-activity relationships of such derivatives led, through a ligand-based approach, to the identification of endogenous long-chain fatty acid ethanolamides or primary amides acting as TRPV2 antagonists. Both synthetic and endogenous antagonists exhibited differential inhibition against known TRPV2 agonists characterized by distinct kinetic profiles. These findings represent the first example of both synthetic and naturally occurring TRPV2 modulators with efficacy in the submicromolar/low-micromolar range, which will be useful for clarifying the physiopathological roles of this receptor, its regulation, and its targeting in pathological conditions.
