73709-21-4

Upstream product

• 1627898-18-3 4,6-dimethoxy-2-[(4-nitrophenyl)amino]pyrimidine 
• 586-78-7 para-nitrophenyl bromide 
• 420-04-2 CYANAMID 
• 100-01-6 4-nitro-aniline 

Downstream Products

• 81093-47-2 4,6-dimethyl-N-(4-nitrophenyl)-2-pyrimidinamine 
• 81093-54-1 4,5,6-Trimethyl-2-(4-nitroanilino)pyrimidin 
• 81093-50-7 4-Methyl-2-(4-nitroanilino)-6-pentylpyrimidin 
• 81093-49-4 4-Butyl-6-methyl-2-(4-nitroanilino)pyrimidin 
• 81093-48-3 4-Ethyl-6-methyl-2-(4-nitroanilino)pyrimidin 
• 81093-51-8 4-Isobutyl-6-methyl-2-(4-nitroanilino)pyrimidin 
• 81093-52-9 4,6-Diethyl-2-(4-nitroanilino)pyrimidin 
• 81093-53-0 2-(4-Nitroanilino)-4,6-dipropylpyrimidin 

Relevant academic research and scientific papers

Cleavage of 2-(Arylamino)-4,6-dimethoxypyrimidines to yield arylguanidines

A novel method for the synthesis of aryl-substituted guanidines in good overall yields is presented; it consists of the acidic cleavage of 2-(arylamino)-4,6-dimethoxypyrimidines, which were prepared by coupling aryl bromides with 2-amino-4,6-dimethoxypyrimidine. This methodology introduces a new means of protection for the guanidine functionality. Copyright

Formation of pyrimidin-2-ylcyanamide and 2-aminopyrimidine in the reaction of aniline derivatives with cyanamide and dimethylamino-1-pyridyl-2-propenone

Substituted o- and p-nitroanilines and m-benzylaminoanilines in the reaction with cyanamide failed to yield the corresponding arylguanidines, and in the presence of 3-dimethylamino-1-(3-pyridyl)-2-propen-1-one formed 4-pyridyl-substituted pyrimidin-2-ylcyanamides and 2-amino-pyrimidines.