73723-49-6

Upstream product

• 1193-55-1 2-methylcyclohexane-1,3-dione 
• 37457-15-1 3-isobutoxy-2-methyl-2-cyclohexen-1-one 
• 74-88-4 methyl iodide 

Downstream Products

• 143008-65-5 2,4-dimethyl-3-(3-methyl-3-butenyl)-2-cyclohexen-1-one 
• 22070-24-2 2,3,4-trimethyltricyclohex-2-en-1-one 
• 20990-14-1 2,4-dimethyl-1,3-cyclohexanedione 
• 143008-88-2 3-[(1R,2R,4aR,7S,8R,8aR)-2,7,8a-Trimethyl-3-oxo-8-(3-oxo-butyl)-decahydro-naphthalen-1-yl]-propionaldehyde 
• 143008-88-2 3-[(1R,2S,4aR,7S,8R,8aR)-2,7,8a-Trimethyl-3-oxo-8-(3-oxo-butyl)-decahydro-naphthalen-1-yl]-propionaldehyde 
• 143008-97-3 (3aRS,4RS,5aSR,8RS,9SR,9aSR,9bRS)-dodecahydro-4-hydroxy-8,9a-dimethyl-9-(3-methyl-3-butenyl)-2-methylene-3aH-benzindene-3a-methanol 3a-p-toluenesulfonate 
• 143008-80-4 (4aRS,5RS,6SR,8aRS)-4a,5,6,7,8,8a-hexahydro-4a,6-dimethyl-5-(3-methyl-3-butenyl)-3-(phenylthio)-2(1H)-naphthalenone 
• 143008-79-1 (3SR,4aRS,5RS,6SR,8aRS)-octahydro-4a,6-dimethyl-5-(3-methyl-3-butenyl)-3-(phenylsulfinyl)-2(1H)-naphthalenone 
• 143008-78-0 (3SR,4aRS,5RS,6SR,8aRS)-octahydro-4a,6-dimethyl-5-(3-methyl-3-butenyl)-1-(phenylthio)-2(1H)-naphthalenone 
• 143008-77-9 (3SR,4aRS,5RS,6SR,8aRS)-octahydro-4a,6-dimethyl-5-(3-methyl-3-butenyl)-3-(phenylthio)-2(1H)-naphthalenone 
• 143008-67-7 2,4-dimethyl-3-(3-methyl-3-butenyl)cyclohexan-1-one 
• 22471-56-3 racemic ishwarone 
• 73723-53-2 3-(3,4-epoxy-3-methylbutyl)-2,3,4-trimethylcyclohexanone 
• 73723-52-1 2,3,4-trimethyl-3-(3-methyl-3-butenyl)cyclohexanone 

Relevant academic research and scientific papers

Catalytic enantioselective approach to the eudesmane sesquiterpenoids: Total synthesis of (+)-carissone

(Chemical Equation Presented) A catalytic enantioselective approach to the eudesmane sesquiterpenoids is reported. The strategic use of a palladium-catalyzed enantioselective alkylation of vinylogous ester substrates forged the C(10) all-carbon quaternary

Application of palladium-catalyzed [3 + 2] cycloaddition technology to the elaboration of kempane diterpenes. Stereocontrolled Synthesis of (±)-3α-hydroxy-7β-kemp-8(9)-en-6-one and (±)-3β-hydroxykemp-7(8)-en-6-one

The total synthesis of three hydroxykempenones (8-10) has been accomplished. The retrosynthetic elements of the strategy focused on setting four key stereocenters in rings A and B, followed by annulation of ring C and ultimate cyclization to construct the seven-membered ring, D. Since the target molecule carries eight contiguous stereogenic centers, proper attention to stereocontrolled processes was mandatory. The key features of the scheme include the palladium-catalyzed [3 + 2] cycloaddition of trimethylenemethane to an activated octalone with complete control of π-facial selectivity, fully regiospecific monooxidation of a diol with ammonium molybdate uniquely at the secondary site to provide a key hydroxy ketone, hydroxyl-directed hydride reduction of the latter intermediate in order to override a contrary kinetic preference for nucleophilic attack, avoidance of Grob fragmentation in diaxial, monofunctionalized 1,3-diols, and selective deoxygenation of a 1,3-diol. The stereochemical results featured in the cycloaddition step were elucidated preliminarily in experiments designed to probe cyclopentannulation in general. The striking kinetic stability of the α,β- and β,γ-unsaturated tetracyclic end products has been analyzed by means of molecular modeling.

Synthesis of β-chloro, β-bromo, and β-iodo α,β-unsaturated ketones

A new, efficient method for the preparation of β-chloro, β-bromo, and β-iodo α,β-unsaturated ketones is described.The method involves the reaction of β-diketones or α-hydroxymethylenecycloalkanones with triphenylphosphine dihalides in the presence of trie