73742-16-2Relevant academic research and scientific papers
COMPOUNDS USEFUL AS MODULATORS OF TRPM8
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Paragraph 0570, (2016/03/29)
The present invention includes compounds useful as modulators of TRPM8, such as compounds of Formulae (Ia), (Ib) and (Ic), and the subgenus and species thereof; personal products containing those compounds; and the use of those compounds and the personal products, particularly the use of increasing or inducing chemesthetic sensations, such as cooling or cold sensations.
Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis
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, (2008/06/13)
Compounds of the formula: where the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picomaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with one or more picomaviruses, such as RVP. Intermediates and synthetic methods for preparing such compounds are also described.
Synthesis of 1,2-dihydropyrrolo[1,2-c]pyrimidin-l-ones
Alvarez, Mercedes,Fernandez, David,Joule, John A.
, p. 249 - 255 (2007/10/03)
1,2-Dihydropyrrolo[1,2-c]pyrimidin-1-ones 2 have been synthesised from pyrrole. We have developed a versatile procedure for the introduction of substituents into the pyrrolopyrimidinones 2, at positions 5 or 7 as desired, and as required by our plans for
