73758-54-0

Basic information

• Product Name: 2-Chloro-2-methylbutyric acid
• Synonyms: 2-Chloro-2-methylbutyric acid
• CAS NO: 73758-54-0
• Molecular Formula: C₅H₉ClO₂
• Molecular Weight: 136.5768
• Mol File: 73758-54-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 181.12°C (rough estimate)
• Flash Point: 81°C
• Appearance: /
• Density: 1.1204
• Vapor Pressure: 0.0768mmHg at 25°C
• Refractive Index: 1.4445
• CAS DataBase Reference: 2-Chloro-2-methylbutyric acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-2-methylbutyric acid(73758-54-0)
• EPA Substance Registry System: 2-Chloro-2-methylbutyric acid(73758-54-0)

Safety Data

• Hazardous Substances Data: 73758-54-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C5H9ClO2/c1-3-5(2,6)4(7)8/h3H2,1-2H3,(H,7,8)

Upstream product

• 408319-68-6 2-chloro-2-methylbutanenitrile 
• 116-53-0 2-Methylbutanoic acid 
• 96-17-3 2-Methylbutyraldehyde 
• 4111-08-4 2-hydroxy-2-methyl-butyronitrile 
• 33212-22-5 2-chloro-2-methylbutyraldehyde 

Downstream Products

• 80-59-1 Tiglic acid 

Relevant articles and documents

The synthesis of the optically active form of the C-18 Cecropia juvenile hormone.

-

Chlorination of Carboxylic Acid Derivatives. VIII. Liquid Phase Chlorination of the Aliphatic C5-Carboxylic Acids and Their Chlorides, Methyl Esters and Chloromethyl Esters with Chlorine

The chlorination of pentanoic, 3-methylbutanoic, 2-methylbutanoic and 2,2-dimethylpropanoic acids and their derivatives with chlorine in the liquid phase have been investigated.The monochloro products formed were determined by gas-liquid chromatography (GLC) and gas-liquid chromatography-mass spectrometry (GLC-MS) as their esters through the comparison with authentic samples.The deactivation of position 2 decreases in the order COCl > CO2H > CO2CH2Cl > CO2CH3, the effect of the COCl-group in pentanoic acid derivatives being 4.3 times stronger than that of the CO2CH3-group.The deactivation is smallest in 2-methylbutanoic acid derivatives owing to the electron-donating methyl group.The EI mass spectra of the methyl and chloromethyl esters have been studied in detail.