7377-75-5

Basic information

• Product Name: 2-Propenoic acid, 3-(phenylamino)-, methyl ester
• Synonyms: 3-anilino-acrylic acid methyl ester;methyl 3-(phenylamino)acrylate;3-Phenylimino-propionsaeure-methylester;Methyl 2-anilinopropenoate;3-Anilino-acrylsaeure-methylester
• CAS NO: 7377-75-5
• Molecular Formula: C10H11NO2
• Molecular Weight: 177.203
• Mol File: 7377-75-5.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 2-Propenoic acid, 3-(phenylamino)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid, 3-(phenylamino)-, methyl ester(7377-75-5)
• EPA Substance Registry System: 2-Propenoic acid, 3-(phenylamino)-, methyl ester(7377-75-5)

Safety Data

• Hazardous Substances Data: 7377-75-5(Hazardous Substances Data)

Upstream product

• 292638-85-8 acrylic acid methyl ester 
• 62-53-3 aniline 
• 265093-28-5 2-Methoxycarbonyl-2-dimethylphenylsilyl-1-phenylaziridine 
• 922-67-8 propynoic acid methyl ester 

Downstream Products

• 5315-72-0 methyl 1-phenyl-1H-1,2,3-triazole-5-carboxylate 
• 1415507-28-6 (Z)-methyl 2-((1H-indol-3-yl)(p-methylphenyl)methyl)-3-phenylaminoacrylate 
• 1415507-27-5 (Z)-methyl 2-((1H-indol-3-yl)(p-methoxyphenyl)methyl)-3-phenylaminoacrylate 
• 1312205-04-1 C₂₀H₁₈N₄O₅ 
• 1312205-03-0 C₂₀H₁₈ClN₃O₃ 
• 1312204-69-5 C₂₁H₁₉N₃O₂ 

Relevant articles and documents

Povarov reaction of β-enamino esters and isatin-3-imines for diastereoselective synthesis of spiro[indoline-3,2′-quinolines]

The p-toluenesulfonic acid catalyzed Povarov reaction of isatin-3-imines with β-enamino esters, which were generated in situ from the reaction of arylamines and methyl propiolate in ethanol, afforded the polysubstituted spiro[indoline-3,2′-quinolines] in

Preparation method of tadalafil impurity G (by machine translation)

The preparation method G of the compound. compound :S1. compound 6 and the reagent, has the advantages that 7;S2. compound 7 reacts with ammoniation reagents and split Pictet - Spengler to give compound, compounds 8;S3. through 8 reaction, and compound 9;S4. compound 9 obtained through acylation reaction, is obtained through acylation reaction of Compound No. 10, with methotreonaldehyde, to obtain compound G; and the preparation method disclosed by the invention is cheap and easy to obtain impurities 6, in whole preparation. 7, The preparation method disclosed by the invention is very cheap and easy to obtain 8, 9, The preparation method disclosed by the invention is cheap and easy to obtain a finished product 10 with high G yield. The whole preparation method is simple, The, preparation method disclosed by the invention is very cheap and easily available, in the whole preparation process shown in the following general ; The preparation method, 95% is, simple 80%, experiment conditions . obtained by acylation reaction of Compound,containing Compound . The preparation method disclosed by the invention is shown below. (by machine translation)

Three-Component Synthesis of Quinolines Based on Radical Cascade Visible-Light Photoredox Catalysis

Synthesis of highly substituted quinolines has been developed based on three-component radical cascade based on visible-light photoredox catalysis. This tandem coupling reaction has been coordinated to proceed with high chemoselectivity based on the differential electronic properties of coupling partners. Subjection of electron-rich β-aminoacrylates with electron-deficient halides and alkenes to the optimized conditions leads to the formation of quinolines in good yields after in situ oxidation of tetrahydroquinolines. Detailed mechanistic studies which reveal an unexpected reaction pathway is described. (Figure presented.).