73770-36-2Relevant academic research and scientific papers
Au(I)-catalyzed tandem [3,3]-sigmatropic rearrangement-cycloisomerization cascade as a route to spirocyclic furans
Yeom, Hyun-Suk,Yoon, Suk-Jae,Shin, Seunghoon
, p. 4817 - 4820 (2008/02/05)
Gold-catalyzed reaction of 1-(3-hydroxypropynyl)cycloalkanol derivatives was studied. The reaction profile was highly dependent on the ring size, migrating group, as well as reaction conditions. An efficient route to spirocyclic furans via tandem [3,3]-si
Pyrrole Annulation onto Aldehydes and Ketones via Palladium-Catalyzed Reactions
Trost, Barry M.,Keinan, Ehud
, p. 2741 - 2746 (2007/10/02)
α-Dicarbonyl systems reacted with vinylmagnesium bromide and acetic anhydride to give α-acetoxy-α-vinylalkanones.These substrates react with benzylamine in the presence of tetrakis(triphenylphosphine)palladium to give N-benzylpyrroles with substituents in the two and/or three position.The functiodifferentiated synthesis of α-dicarbonyl compounds from ketones makes this a pyrrole annulation onto any α-methylene carbonyl system.
