737767-06-5Relevant academic research and scientific papers
New carborane-containing amino acids and their derivatives. Crystal structures of n-protected carboranylalaninates
Timofeev,Bregadze,Osipov,Titanyuk,Petrovskii,Starikova,Glukhov,Beletskaya
, p. 791 - 797 (2007)
New alanine derivatives containing both the carboranyl and trifluoromethyl groups were synthesized by the reaction of organometallic derivatives of o-carborane with methyl trifluoropyruvate imines. When using the 1R-(-)-menthoxycarbonyl protecting group at the nitrogen atom, one of diastereomers was isolated and characterized. Trifluoromethyl-carboranylalanine methyl esters containing different protecting groups at the nitrogen atom were studied by X-ray diffraction. Both complete and partial deprotection of the amino and carboxy groups was performed.
