737788-41-9Relevant academic research and scientific papers
Synthesis of a Lipomannan Component of the Cell-Wall Complex of Mycobacterium tuberculosis Is Based on Paulsen's Concept of Donor/Acceptor "Match"
Jayaprakash,Lu, Jun,Fraser-Reid, Bert
, p. 5894 - 5898 (2005)
The perfect match: A mannosidyl n-pentenylorthoester 1 is the sole donor and acceptor source for a branched oligomannan array (see picture). An iterative process of regioselective glycosidation of polyol acceptors virtually eliminates the need for protect
Synthesis of a key Mycobacterium tuberculosis biosynthetic phosphoinositide intermediate
Jayaprakash,Lu, Jun,Fraser-Reid, Bert
, p. 3815 - 3819 (2007/10/03)
Regioselective mannosylations of a myoinositol acceptor diol are readily achieved by Lewis acid mediated iodinolysis of n-pentenyl ortho-esters. The procedure affords a psuedotrisaccharide to which the phosphoglyceryl and other lipid residues are added le
