737800-08-7

Upstream product

• 737800-07-6 2-[3,5-bis-benzyloxy-2-(tert-butyl-diphenyl-silanyloxymethyl)-6-(3-methyl-but-2-enyl)-phenyl]-4,4-dimethyl-4,5-dihydro-oxazole 
• 870-63-3 prenyl bromide 
• 737800-16-7 [4,6-bis-benzyloxy-2-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-3-(3-methyl-but-2-enyl)-phenyl]-methanol 
• 737800-06-5 4,6-bis-benzyloxy-2-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-3-(3-methyl-but-2-enyl)-benzoic acid methyl ester 

Downstream Products

• 737800-15-6 4,6-bis-benzyloxy-2-(3,5-dichloro-2-hydroxy-6-methoxy-4-methyl-benzoyl)-3-(3-methyl-but-2-enyl)-benzaldehyde 
• 737800-14-5 4,6-bis-benzyloxy-2-(3,5-dichloro-2,6-dihydroxy-4-methyl-benzoyl)-3-(3-methyl-but-2-enyl)-benzaldehyde 
• 737800-13-4 4,6-bis-benzyloxy-2-(3,5-dichloro-2,6-bis-methoxymethoxy-4-methyl-benzoyl)-3-(3-methyl-but-2-enyl)-benzaldehyde 
• 737800-12-3 [3,5-bis-benzyloxy-2-hydroxymethyl-6-(3-methyl-but-2-enyl)-phenyl]-(3,5-dichloro-2,6-bis-methoxymethoxy-4-methyl-phenyl)-methanol 
• 737800-10-1 [3,5-bis-benzyloxy-2-(tert-butyl-diphenyl-silanyloxymethyl)-6-(3-methyl-but-2-enyl)-phenyl]-(3,5-dichloro-2,6-bis-methoxymethoxy-4-methyl-phenyl)-methanone 
• 1026582-55-7 [3,5-bis-benzyloxy-2-(tert-butyl-diphenyl-silanyloxymethyl)-6-(3-methyl-but-2-enyl)-phenyl]-(3,5-dichloro-2,6-bis-methoxymethoxy-4-methyl-phenyl)-methanol 

Relevant academic research and scientific papers

The first total synthesis of SB87-Cl and pestalone, novel bioactive benzophenone natural products

SB87-Cl 1, an inhibitor of testosterone-5α-reductase, and pestalone 2 exhibiting effective antimicrobial activity against MRSA (MIC=37ng/mL) and VRE (MIC=78ng/mL), were novel bioactive benzophenone natural products. Total synthesis of 1 and 2 has been successfully accomplished. The common synthetic precursor 18 of 1 and 2, was successfully obtained by the coupling of 8 with 12.